1233402-94-2

Basic information

• Product Name: N₁-(4-hydroxyphenyl)-2-[(4-hydroxyanilino)sulfonyl]benzamide
• CAS NO: 1233402-94-2
• Molecular Weight: 384.412
• Mol File: 1233402-94-2.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: N₁-(4-hydroxyphenyl)-2-[(4-hydroxyanilino)sulfonyl]benzamide(CAS DataBase Reference)
• NIST Chemistry Reference: N₁-(4-hydroxyphenyl)-2-[(4-hydroxyanilino)sulfonyl]benzamide(1233402-94-2)
• EPA Substance Registry System: N₁-(4-hydroxyphenyl)-2-[(4-hydroxyanilino)sulfonyl]benzamide(1233402-94-2)

Safety Data

• Hazardous Substances Data: 1233402-94-2(Hazardous Substances Data)

Upstream product

• 34684-21-4 2-chlorosulfonylbenzoyl chloride 
• 123-30-8 4-amino-phenol 

Relevant articles and documents

Synthesis of a few cyclothiadiazanones and aminosulfonyl benzamides from saccharin

Saccharin is hydrolyzed with two different acids to yield 1,2-di-acid. The di-acid, on chlorination with phosphorous pentachloride, gave 2-chlorosulfonylbenzoyl chloride. The 2-chlorosulfonylbenzoyl chloride on hydrazinolysis gave benzothiadiazinetrione, while with phenyl hydrazine it selectively yielded 2-phenylbenzothiadiazinetrione. 2-chlorosulfonoylbenzoyl chloride with different aromatic 1,2- diamines resulted in dibenzothiadiazocine derivatives. Electron-donating groups in the diamine facilitate while the electron-withdrawing groups retard the cyclization. However, aliphatic diamines, aniline and substituted anilines readily gave acyclic aminosulfonyl carboxybenzamides on condensation with 2- chlorosulfonylbenzoyl chloride. The di-acid and anhydride did not react with either hydrazine/phenyl hydrazine or amines to give the above products. However, when its ester derivative, isopropyl-2- chlorosulfonylbenzoate, condensed with hydrazine, it gave benzothiadiazinetrione. But the ester failed to react with phenyl hydrazine. All the condensation reactions were carried out at room temperature.