123343-92-0

Basic information

• Product Name: N-(5-amino-2-methoxyphenyl)methanesulfonamide
• CAS NO: 123343-92-0
• Molecular Formula: C₈H₁₂N₂O₃S
• Molecular Weight: 216.2575
• Mol File: 123343-92-0.mol
• Article Data: 4

Chemical Properties

• Boiling Point: 394.146°C at 760 mmHg
• Flash Point: 192.173°C
• Density: 1.384g/cm³
• Vapor Pressure: 0mmHg at 25°C
• Refractive Index: 1.605
• CAS DataBase Reference: N-(5-amino-2-methoxyphenyl)methanesulfonamide(CAS DataBase Reference)
• NIST Chemistry Reference: N-(5-amino-2-methoxyphenyl)methanesulfonamide(123343-92-0)
• EPA Substance Registry System: N-(5-amino-2-methoxyphenyl)methanesulfonamide(123343-92-0)

Safety Data

• Hazardous Substances Data: 123343-92-0(Hazardous Substances Data)

Upstream product

• 80259-06-9 3-(methanesulfonamido)-4-methoxynitrobenzene 
• 99-59-2 3-amino-4-methoxynitrobenzene 

Downstream Products

• 870090-66-7 3-methoxy-4-nitro-N-(3-methanesulfonylamino-4-methoxyphenyl)benzamide 
• 508212-99-5 N-{5-[({[4-(Benzhydryloxy)-3-isobutyrylphenyl]amino}carbonyl)amino]-2-methoxyphenyl}methane sulfonamide 

Relevant articles and documents

SUBSTITUTED N-ARYL BENZAMIDES AND RELATED COMPOUNDS FOR TREATMENT OF AMYLOID DISEASES AND SYNUCLEINOPATHIES

Substituted diaryl compounds of the Formulae (I, II, III), where the variables are as defined in the claims, and their pharmaceutically acceptable derivatives, their synthesis, pharmaceutical compositions containing them, and their use in the treatment of amyloid diseases, including A? amyloidosis, such as observed in Alzheimer's disease, IAPP amyloidosis, such as observed in type 2 diabetes, and synucleinopathies, such as observed in Parkinson's disease, and the manufacture of medicaments for such treatment are provided.

Synthesis of pyrrolo[4,3,2-de]quinolines from 6,7-dimethoxy-4-methylquinoline. Formal total syntheses of damirones A and B, batzelline C, isobatzelline C, discorhabdin C, and makaluvamines A-D

2-Amino-4-nitrophenol and 2-methoxy-5-nitroaniline were converted into the 5-nitroquinolines 6b and 6d, respectively, and then the latter into nitro-acetal 6f. 6,7-Dimethoxy-4-methylquinoline (6g) was nitrated at C-5 and then the methyl substituent conver