123343-99-7

Basic information

• Product Name: N-(2-FLUORO-5-NITROPHENYL)METHANESULFONAMIDE
• Synonyms: N-(2-FLUORO-5-NITROPHENYL)METHANESULFONAMIDE
• CAS NO: 123343-99-7
• Molecular Formula: C₇H₇FN₂O₄S
• Molecular Weight: 234.206
• Mol File: 123343-99-7.mol
• Article Data: 6

Chemical Properties

• Melting Point: 163-165°
• Boiling Point: 348.2±52.0 °C(Predicted)
• Appearance: /
• Density: 1.604±0.06 g/cm3(Predicted)
• PKA: 5.96±0.10(Predicted)
• CAS DataBase Reference: N-(2-FLUORO-5-NITROPHENYL)METHANESULFONAMIDE(CAS DataBase Reference)
• NIST Chemistry Reference: N-(2-FLUORO-5-NITROPHENYL)METHANESULFONAMIDE(123343-99-7)
• EPA Substance Registry System: N-(2-FLUORO-5-NITROPHENYL)METHANESULFONAMIDE(123343-99-7)

Safety Data

• HazardClass: IRRITANT
• Hazardous Substances Data: 123343-99-7(Hazardous Substances Data)

Usage

General Description

N-(2-Fluoro-5-nitrophenyl)methanesulfonamide is a chemical compound that belongs to the class of sulfonamides, which are organic compounds containing a sulfur atom bonded to three oxygen atoms (a sulfonamide group) and an amine group. It is a white to off-white crystalline solid with the molecular formula C7H7FN2O4S. N-(2-FLUORO-5-NITROPHENYL)METHANESULFONAMIDE is used in the field of medicinal chemistry, particularly in the development of pharmaceuticals. Its structure and properties make it a valuable building block for the synthesis of various biologically active molecules and potential drug candidates. Additionally, it exhibits antimicrobial and antifungal properties, making it a potential candidate for the development of new antibiotics and antifungal agents.

Upstream product

• 369-36-8 6-fluoro-3-nitroaniline 
• 124-63-0 methanesulfonyl chloride 

Downstream Products

• 157921-53-4 N-(2-Fluoro-5-nitro-phenyl)-N-methyl-methanesulfonamide 
• 253339-77-4 2'-[2-(isopropylamino)ethoxy]-5'-nitromethanesulfonanilide 
• 150779-46-7 N-(2-cyclohexyloxy-5-nitrophenyl)methanesulfonamide 
• 51765-49-2 N-(5-nitro-2-phenoxyphenyl)methanesulfonamide 
• 123343-90-8 N-(5-amino-2-fluorophenyl)methanesulfonamide 

Relevant articles and documents

AMINOPYRAZOLE DERIVATIVES

An objective of the present invention is to provide low-molecular-weight compounds that can inhibit Src family kinases. The present invention relates to compounds represented by general formula (I) or pharmacologically acceptable salts thereof. In the formula, Ar1 is optionally substituted C6-10 arylene or 5- to 10-membered heteroarylene, and Ar2 is optionally substituted C6-10 aryl or 5- to 10-membered heteroaryl. R1 and R2 are defined as described in the specification.

5-aminoacetylaminosulfonanilide compounds

The present compounds represented by the formula: STR1 (wherein R1 is a phenyl group, a halophenyl group or a cycloalkyl group having 3 to 8 carbon atoms, R2 is a hydrogen atom or an alkyl group having 1 to 5 carbon atoms, R3 is a hydrogen atom, an alkyl group having 1 to 7 carbon atoms, a cycloalkyl group having 3 to 8 carbon atoms, an alkenyl group having 3 to 5 carbon atoms or a benzyl group, or R2 and R3 are bonded together to form a 5- to 7-membered heterocycle) and salts thereof have potent anti-inflammatory, antipyretic, analgesic and anti-allergic actions with less side effects such as gastrointestinal disorders and with such a high safety as to permit long-term administration.

5-aminosulfonanilide compounds

5-Aminosulfonanilide compounds represented by the formula: STR1 (wherein R is a hydrogen atom, a formyl group, an acetyl group, a propionyl group, an n-butyryl group, an n-valeryl group, an ethoxyoxalyl group, an n-propoxyoxalyl group, a methoxycarbonylac