1233498-33-3

Basic information

• Product Name: (-)-leucoridine C
• Synonyms: (-)-leucoridine C
• CAS NO: 1233498-33-3
• Molecular Weight: 574.809
• Mol File: 1233498-33-3.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: (-)-leucoridine C(CAS DataBase Reference)
• NIST Chemistry Reference: (-)-leucoridine C(1233498-33-3)
• EPA Substance Registry System: (-)-leucoridine C(1233498-33-3)

Safety Data

• Hazardous Substances Data: 1233498-33-3(Hazardous Substances Data)

Upstream product

• 18397-07-4 (+)-geissoschizoline 
• 2912-08-5 (-)-19,20-dihydroakuammicine 
• 639-43-0 (-)-akuammicine 
• 1233498-30-0 (16S)-1,17-(1,2-dehydro-curan-17,16-diyl)-curane-2⁽¹⁶⁾-ene 
• 7267-97-2 curan-17-oic acid methyl ester 

Relevant articles and documents

Biomimetic total syntheses of (-)-leucoridines A and C through the dimerization of (-)-dihydrovalparicine

Concise biomimetic syntheses of the Strychnos-Strychnos-type bis-indole alkaloids (-)-leucoridine A (1) and C (2) were accomplished through the biomimetic dimerization of (-)-dihydrovalparicine (3). En route to 3, the known alkaloids (+)-geissoschizoline (8) and (-)-dehydrogeissoschizoline (10) were also prepared. DFT calculations were employed to elucidate the mechanism, which favors a stepwise aza-Michael/spirocyclization sequence over the alternate hetero-Diels-Alder cycloaddition reaction. Concise biomimetic syntheses of the Strychnos-Strychnos-type bis-indole alkaloids (-)-leucoridine A and C were accomplished through the biomimetic dimerization of (-)-dihydrovalparicine. DFT calculations were used to elucidate the mechanism, which favors a stepwise aza-Michael/spirocyclization sequence over the alternate hetero-Diels-Alder cycloaddition reaction.