1233503-31-5

Basic information

• Product Name: 4,6-dimethyl-2-((4R,5S)-4-methyl-2-oxo-5-phenyloxazolidin-3-yl)nicotinonitrile
• Synonyms: 4,6-dimethyl-2-((4R,5S)-4-methyl-2-oxo-5-phenyloxazolidin-3-yl)nicotinonitrile
• CAS NO: 1233503-31-5
• Molecular Weight: 307.352
• Mol File: 1233503-31-5.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: 4,6-dimethyl-2-((4R,5S)-4-methyl-2-oxo-5-phenyloxazolidin-3-yl)nicotinonitrile(CAS DataBase Reference)
• NIST Chemistry Reference: 4,6-dimethyl-2-((4R,5S)-4-methyl-2-oxo-5-phenyloxazolidin-3-yl)nicotinonitrile(1233503-31-5)
• EPA Substance Registry System: 4,6-dimethyl-2-((4R,5S)-4-methyl-2-oxo-5-phenyloxazolidin-3-yl)nicotinonitrile(1233503-31-5)

Safety Data

• Hazardous Substances Data: 1233503-31-5(Hazardous Substances Data)

Upstream product

• 77943-39-6 4-methyl-5-phenyloxazolidin-2-one 
• 1174281-26-5 3-cyano-4,6-dimethyl-2-pyridinyl tosylate 

Relevant articles and documents

Pd-catalyzed C-N bond formation with heteroaromatic tosylates

A protocol for the palladium(0)-catalyzed amidation of heteroaromatic tosylates was successfully developed. The methodology proved to be effective for a variety of heteroaryl tosylates including the pyridine, pyrimidine, quinoline and quinoxaline ring systems. Successful carbon-nitrogen bond formation with these heteroaryl tosylates could be performed with a wide range of primary amides, oxazolidinones, lactams, anilines and indoles, including one cyclic urea. Moreover, this C-N bond forming reaction provided products with high structural diversity. The coupling reaction was also amenable to scale up applications.