123372-13-4 Usage
Description
(S)-(-)-O-DESMETHYLCARVEDILOL is an optically active metabolite of Carvedilol, a nonselective β-adrenergic blocker with α1-blocking activity. It is characterized by its off-white solid appearance and exhibits optical activity with a specific rotation of [α]D= -18.7 (c= 0.1 methanol).
Uses
Used in Pharmaceutical Industry:
(S)-(-)-O-DESMETHYLCARVEDILOL is used as a pharmaceutical compound for its potential therapeutic applications. As a metabolite of Carvedilol, it may contribute to the drug's overall efficacy and safety profile in the treatment of various cardiovascular conditions, such as hypertension, angina, and heart failure. Its α1-blocking activity may also play a role in providing additional benefits in managing blood pressure and improving cardiovascular function.
Check Digit Verification of cas no
The CAS Registry Mumber 123372-13-4 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 1,2,3,3,7 and 2 respectively; the second part has 2 digits, 1 and 3 respectively.
Calculate Digit Verification of CAS Registry Number 123372-13:
(8*1)+(7*2)+(6*3)+(5*3)+(4*7)+(3*2)+(2*1)+(1*3)=94
94 % 10 = 4
So 123372-13-4 is a valid CAS Registry Number.
InChI:InChI=1/C23H24N2O4/c26-16(14-24-12-13-28-21-10-4-3-9-20(21)27)15-29-22-11-5-8-19-23(22)17-6-1-2-7-18(17)25-19/h1-11,16,24-27H,12-15H2/t16-/m1/s1
123372-13-4Relevant articles and documents
STORE OVERLOAD-INDUCED CALCIUM RELEASE INHIBITORS AND METHODS FOR PRODUCING AND USING THE SAME
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Sheet 1/7, (2015/03/16)
The present invention provides compounds having store overload-induced Ca2+ release (SOICR) inhibitory activity and methods for producing and using the same. In particular, compounds of the invention is of the formula: R1-X1-L-X2-R2, wherein R1, X1, L, X2, and R2 are those defined herein.