123409-81-4

Basic information

• Product Name: 10bR-1,2,3,5,6,10bβ-hexahydro-6-phenylpyrrolo<2,1-a>isoquinoline
• CAS NO: 123409-81-4
• Molecular Weight: 249.356
• Mol File: 123409-81-4.mol
• Article Data: 10

Chemical Properties

• CAS DataBase Reference: 10bR-1,2,3,5,6,10bβ-hexahydro-6-phenylpyrrolo<2,1-a>isoquinoline(CAS DataBase Reference)
• NIST Chemistry Reference: 10bR-1,2,3,5,6,10bβ-hexahydro-6-phenylpyrrolo<2,1-a>isoquinoline(123409-81-4)
• EPA Substance Registry System: 10bR-1,2,3,5,6,10bβ-hexahydro-6-phenylpyrrolo<2,1-a>isoquinoline(123409-81-4)

Safety Data

• Hazardous Substances Data: 123409-81-4(Hazardous Substances Data)

Upstream product

• 87519-83-3 (6R,10bR)-6-Phenyl-1,2,3,5,6,10b-hexahydro-pyrrolo[2,1-a]isoquinoline; hydrochloride 
• 56523-47-8 (R)-2-phenylpyrrolidine 
• 96-09-3 styrene oxide 
• 3963-62-0 2,2-Diphenylethylamine 
• 1006-64-0 2-(phenyl)pyrrolidine 
• 73691-20-0 6-Phenyl-1,5,6,10b-tetrahydro-2H-pyrrolo[2,1-a]isoquinolin-3-one 
• 96786-35-5 1,2,3,5,6,10b-hexahydro-6-phenylpyrrolo<2,1-a>isoquinolin-6-ol hydrobromide 
• 96786-35-5 (6S,10bS)-6-Phenyl-1,2,3,5,6,10b-hexahydro-pyrrolo[2,1-a]isoquinolin-6-ol; hydrobromide 
• 73691-13-1 1-(2,2-Diphenyl-ethyl)-5-ethoxy-pyrrolidin-2-one 
• 87519-56-0 1-(2,2-diphenylethyl)pyrrolidine-2,5-dione 

Downstream Products

• 87519-83-3 (6R,10bR)-6-Phenyl-1,2,3,5,6,10b-hexahydro-pyrrolo[2,1-a]isoquinoline; hydrochloride 
• 90457-59-3 (6S,10bR)-6-Phenyl-1,2,3,5,6,10b-hexahydro-pyrrolo[2,1-a]isoquinoline 
• 90457-60-6 1,2,3,5,6,10bβ-hexahydro-6α-phenylpyrrolo<2,1-a>isoquinoline 

Relevant articles and documents

Resolution and absolute configuration of 1,2,3,5,6,10bβ-hexahydro-6α-phenylpyrrolo[2,1-a]isoquinoline (McN-4612-Z). A problem of determination of the enantiomeric purity for a tertiary amine

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Synthetic method of tetrahydroisoquino ring compound and tetrahydro-beta-carbo ring compound

The invention provides a synthetic method of a tetrahydroisoquino ring compound and a tetrahydro-beta-carbo ring compound, and belongs to the technical field of synthesis. According to the method forsynthesizing the tetrahydroisoquino and the tetrahydro-b

Diastereoselective allylation of 3,4-dihydro-4-phenylisoquinoline. Convenient methods for the preparation of cis- and trans-1-allyl-4-phenyl-1,2,3, 4-tetrahydroisoquinoline#

Diastereoselective allylation of 3,4-dihydro-4-phenylisoquinoline by several allylating reagents was examined. Reactions using allyltin or allylsilane in the presence of alkyl chloroformate and a catalytic amount of trimethylsilyl triflate gave trans-1-allyl-4-phenyl-1,2,3,4- tetrahydroisoquinoline with moderate diastereoselectivity. In contrast, cis-1-allyl-4-phenyl-1,2,3,4-tetrahydroisoquinoline was obtained predominantly in the reactions using allyllithium, triallylborane, allylzinc bromide, and diallylzinc. cis-1-Allyl-4-phenyl-1,2,3,4-tetrahydroisoquinoline was transformed to (6S*,10bR*)-hexahydro-6-phenylpyrrolo[2,1-a]isoquinoline, a potential antidepressant agent, in five steps.