123418-70-2

Basic information

• Product Name: 3-Thiophenecarboxylic acid, 4,5-dichloro-
• Synonyms: 3-Thiophenecarboxylic acid, 4,5-dichloro-;4,5-Dichloro-3-thiophenecarboxylic acid;4,5-Dichlorothiophene-3-carboxylic acid
• CAS NO: 123418-70-2
• Molecular Formula: C5H2Cl2O2S
• Molecular Weight: 197.03918
• Mol File: 123418-70-2.mol
• Article Data: 3

Chemical Properties

• Boiling Point: 309.7 °C at 760 mmHg
• Flash Point: 141.1 °C
• Appearance: /
• Density: 1.708 g/cm³
• Vapor Pressure: 0.000272mmHg at 25°C
• Refractive Index: 1.636
• Storage Temp.: 2-8°C(protect from light)
• CAS DataBase Reference: 3-Thiophenecarboxylic acid, 4,5-dichloro-(CAS DataBase Reference)
• NIST Chemistry Reference: 3-Thiophenecarboxylic acid, 4,5-dichloro-(123418-70-2)
• EPA Substance Registry System: 3-Thiophenecarboxylic acid, 4,5-dichloro-(123418-70-2)

Safety Data

• Hazardous Substances Data: 123418-70-2(Hazardous Substances Data)

Usage

General Description

3-Thiophenecarboxylic acid, 4,5-dichloro- is a chemical compound with the molecular formula C6H3Cl2O2S. It is a derivative of thiophene and carboxylic acid, containing two chlorine atoms at the 4 and 5 positions. This chemical is often used as a reagent in organic synthesis and pharmaceutical research. It has the potential to be used as an intermediate in the production of various pharmaceutical compounds due to its structural characteristics and functional groups. 3-Thiophenecarboxylic acid, 4,5-dichloro- may also have potential applications in the development of agrochemicals and materials science. Its properties and functionalities make it an important compound in various scientific and industrial fields.

InChI:InChI=1/C5H2Cl2O2S/c6-3-2(5(8)9)1-10-4(3)7/h1H,(H,8,9)

Upstream product

• 123418-68-8 1-(4,5-Dichlor-3-thienyl)-ethanon 
• 61200-59-7 4,5-dichlorothiophene-3-carbaldehyde 
• 498-62-4 3-thiophene carboxaldehyde 
• 36157-40-1 3-acetyl-2,5-dichlorothiophene 
• 58119-67-8 1-(5-Chlor-3-thienyl)-ethanon 

Relevant articles and documents

Novel thienopyrrole glycogen phosphorylase inhibitors: Synthesis, in vitro SAR and crystallographic studies

Two series of novel thienopyrrole inhibitors of recombinant human liver glycogen phosphorylase a (GPa) which are effective in reducing glucose output from rat hepatocytes are described. Representative compounds have been shown to bind at the dimer interface site of the rabbit muscle enzyme by X-ray crystallography.

Herbicidal Thienylureas, I

Syntheses of the title substances as potential herbicides are described by a modified Curtius degradation of corresponding thiophene carboxylic acids, obtained in turn by haloform reaction of appropriate acetyl thiophenes.Regioselective substitution reactions of thiophenes were key steps for the construction of desired substitution patterns.Structure-activity considerations show that especially the 3-thienyl ureas 36 and 38 exhibit significant herbicidal activity comparable with commercial products. - Keywords: Curtius degradation; Herbicides; Thiophenes; Ureas; Urethanes