123432-00-8

Basic information

• Product Name: Thiophene, 2-[(1E)-2-(phenylthio)ethenyl]-
• CAS NO: 123432-00-8
• Molecular Formula: C12H10S2
• Molecular Weight: 218.343
• Mol File: 123432-00-8.mol
• Article Data: 3

Chemical Properties

• CAS DataBase Reference: Thiophene, 2-[(1E)-2-(phenylthio)ethenyl]-(CAS DataBase Reference)
• NIST Chemistry Reference: Thiophene, 2-[(1E)-2-(phenylthio)ethenyl]-(123432-00-8)
• EPA Substance Registry System: Thiophene, 2-[(1E)-2-(phenylthio)ethenyl]-(123432-00-8)

Safety Data

• Hazardous Substances Data: 123432-00-8(Hazardous Substances Data)

Upstream product

• 874-84-0 2-(2-nitroethenyl)thiophene 
• 108-98-5 thiophenol 
• 477727-73-4 2-(thiophen-2-yl)vinyl bromide 
• 98-03-3 thiophene-2-carbaldehyde 
• 77295-66-0 2-(2,2-dibromovinyl)thiophene 
• 123431-99-2 (Z)-1-bromo-2-(2-thienyl)ethene 
• 17314-33-9 tributyltin phenyl sulfide 
• 123431-99-2 (E)-1-(thiophen-2'-yl)-2-bromoethylene 

Relevant articles and documents

A Simplified Protocol for the Stereospecific Nickel-Catalyzed C-S Vinylation Using NiX 2 Salts and Alkyl Phosphites

A Ni-catalyzed C-S cross-coupling using only NiI 2 (0.5-2.5 molpercent) and P(O i Pr) 3 (2.0-10.0 molpercent) is reported. Using an air-stable Ni(II) precatalyst, and a cheap and commercially available ligand, a scalable and robust method was developed to cross-couple various thiophenols and styryl bromides, including some sterically encumbered thiols, an α-bromocinnamaldehyde as well as a thiolation-cyclization.

PALLADIUM-CATALYZED REACTIONS OF TRIALKYLSTANNYL PHENYL SULFIDES WITH ALKENYL BROMIDES. A NEW DIASTEREOSELECTIVE SYNTHESIS OF (E)-1-ALKENYL PHENYL SULFIDES

The reaction of easily available stereoisomeric mixtures of 1-alkenyl bromides with molar excesses of trialkylstannyl phenyl sulfides takes place readily in the presence of Pd(PPh3)4 to afford diastereoselectively (E)-1-alkenyl phenyl sulfides in excellent yields.