1234342-07-4Relevant articles and documents
Solid-phase synthesis of oligodeoxyribonucleotides without base protection utilizing o-selective reaction of oxazaphospholidine derivatives
Oka, Natsuhisa,Maizuru, Yukihiro,Shimizu, Mamoru,Wada, Takeshi
, p. 144 - 154 (2010)
A study on the development of a novel method to synthesize oligodeoxyribonucleotides without base protection is described. We found that nucleoside 3′-O-oxazaphospholidine derivatives exclusively react with the hydroxy group of nucleosides in the presence