1234421-77-2

Basic information

• Product Name: N,N-dimethyl-2'-(pyridin-2-yl)-[1,1'-biphenyl]-4-amine
• Synonyms: N,N-dimethyl-2'-(pyridin-2-yl)-[1,1'-biphenyl]-4-amine
• CAS NO: 1234421-77-2
• Molecular Weight: 274.365
• Mol File: 1234421-77-2.mol
• Article Data: 7

Chemical Properties

• CAS DataBase Reference: N,N-dimethyl-2'-(pyridin-2-yl)-[1,1'-biphenyl]-4-amine(CAS DataBase Reference)
• NIST Chemistry Reference: N,N-dimethyl-2'-(pyridin-2-yl)-[1,1'-biphenyl]-4-amine(1234421-77-2)
• EPA Substance Registry System: N,N-dimethyl-2'-(pyridin-2-yl)-[1,1'-biphenyl]-4-amine(1234421-77-2)

Safety Data

• Hazardous Substances Data: 1234421-77-2(Hazardous Substances Data)

Upstream product

• 100-10-7 4-dimethylamino-benzaldehyde 
• 1008-89-5 2-phenylpyridine 
• 586-77-6 4-bromo-N,N-dimethylaniline 
• 17997-47-6 2-tri-n-butylstannylpyridine 
• 89346-48-5 2-(2-fluorophenyl)pyridine 
• 95752-87-7 5,5-dimethyl-2-(4-(N,N-dimethylamino)phenyl)-1,3,2-dioxaborinane 
• 501374-30-7 5,5-dimethyl-2-(4-trifluoromethyl-phenyl)-[1,3,2]dioxaborinane 
• 1072-85-1 o-fluorobromobenzene 
• 698-69-1 4-chloro-N,N-dimethylaniline 

Relevant articles and documents

Novel organoruthenium(II) β-diketonates as catalysts for ortho arylation via C-H activation

Five different fluorinated β-diketone ligands in the presence of sodium methoxide easily react with the organoruthenium precursor [(η6-p-cymene)Ru(μ-Cl)Cl]2, generating neutral complexes 1-5 with typical "piano-stool" geometry. All s

Ligand-Tuned C–H Bond Activation/Arylation of 2-Arylpyridines over Pyridine-Based N,O/N,N Ligated Ruthenium–Arene Complexes

Water-soluble ruthenium(II)–arene complexes [(η6-arene)Ru(κ2-L)]n+ (n = 0, 1) ([Ru]-1–[Ru]-10) containing pyridine-based bischelating N,O/N,N donor ligands (L1–L5) are synthesized and employed for the catalytic C–H bond activation/arylation of a wide range of 2-phenylpyridines and aryl halides in water, affording the corresponding mono- and biarylated products. Exploring the reactivity of the synthesized complexes, our investigations, including time-dependent 1H NMR spectroscopic studies with ruthenium–arene catalysts, demonstrate a remarkable structure–activity relationship for the ligand-tuned C–H activation/arylation of 2-phenylpyridine, where the complexes with bischelating N,O donor-based ligands (acteylpyridine and picolinate) outperform those with N,N donor ligands (iminopyridine). Moreover, among the N,O donor ligands, a distinct effect of the nature of the coordinating oxygen donor on the catalytic activity is also observed, where ruthenium–arene complexes having N,O donor ligands (acetylpyridine) with neutral oxygen-donor atoms exhibit enhanced catalytic activity over those with anionic oxygen-donor atoms (picolinate). The observed trend in the catalytic activity is attributed to the ligand-promoted facile deprotonation and coordination–decoordination interconversion behavior. In addition, molecular structures for a few of the representative complexes ([Ru]-2, [Ru]-4, and [Ru]-5) are authenticated by single-crystal X-ray diffraction studies.

Ruthenium(ii)-catalyzed selective monoarylation in water and sequential functionalisations of C-H bonds

The ruthenium(ii)-phosphine catalyst RuCl2(PPh 3)(p-cymene) operating water selectively leads to ortho monoarylation, with arylchlorides and heteroarylhalides, of functional arenes. Further catalytic heteroarylation with Ru(OAc)2(p-cymene) in water produces mixed bifunctional derivatives.