1234504-73-4Relevant articles and documents
Photoinduced addition of glycosyl thiols to alkynyl peptides: Use of free-radical thiol-yne coupling for post-translational double-glycosylation of peptides
Lo Conte, Mauro,Pacifico, Salvatore,Chambery, Angela,Marra, Alberto,Dondoni, Alessandro
, p. 4644 - 4647 (2010)
(Figure presented) Double glycosylation of cysteine-containing peptides has been carried out by a one-pot two-step sequence comprising selective S-propargylation followed by photoinduced (λ max 365 nm) free-radical hydrothiolation with glycosyl thiols. Conditions were established for the sequential introduction of two different thiol residues such as a glycosyl and a biotinyl derivative.