1234847-45-0

Basic information

• Product Name: 7-(Methoxycarbonyl)-2-methyl-1,3-benzoxazole
• Synonyms: 7-(Methoxycarbonyl)-2-methyl-1,3-benzoxazole;Methyl 2-methyl-1,3-benzoxazole-7-carboxylate;ethyl 2-methylbenzo[d]oxazole-7-carboxylate
• CAS NO: 1234847-45-0
• Molecular Formula: C10H9NO3
• Molecular Weight: 191.18336
• Mol File: 1234847-45-0.mol
• Article Data: 3

Chemical Properties

• Boiling Point: 301.7±15.0 °C(Predicted)
• Appearance: /
• Density: 1.205±0.06 g/cm3(Predicted)
• PKA: -0.45±0.30(Predicted)
• CAS DataBase Reference: 7-(Methoxycarbonyl)-2-methyl-1,3-benzoxazole(CAS DataBase Reference)
• NIST Chemistry Reference: 7-(Methoxycarbonyl)-2-methyl-1,3-benzoxazole(1234847-45-0)
• EPA Substance Registry System: 7-(Methoxycarbonyl)-2-methyl-1,3-benzoxazole(1234847-45-0)

Safety Data

• Hazardous Substances Data: 1234847-45-0(Hazardous Substances Data)

Upstream product

• 22621-41-6 2-hydroxy-3-nitro-benzoic acid methyl ester 
• 91-66-7 N,N-diethylaniline 
• 90564-38-8 2-Hydroxy-3-nitrobenzoesaeureethylester 
• 570-23-0 3-aminosalicylic acid 
• 78-39-7 Triethyl orthoacetate 

Relevant articles and documents

GPR120 RECEPTOR AGONISTS AND USES THEREOF

GPR120 agonists are provided. These compounds are useful for the treatment of metabolic diseases, including Type II diabetes and diseases associated with poor glycemic control.

Novel synthesis of benzoxazoles from o-nitrophenols and amines

o-Nitrophenols and o-nitroaniline were reacted with amines at 210-215°C to produce the corresponding benzoxazoles and benzimidazoles, respectively, in moderate yields. The reactions between o-nitrophenols containing a CO2Me or OMe group on their benzene rings and N,N-diethylaniline were examined to investigate the effects of the position and electronic character of these substituents on the formation of the oxazole ring.