123506-55-8

Basic information

• Product Name: 7-Amino-3-methyl-2,4-dioxo-5-phenyl-1,2,3,4-tetrahydro-pyrido[2,3-d]pyrimidine-6-carboxylic acid amide
• Synonyms: 7-Amino-3-methyl-2,4-dioxo-5-phenyl-1,2,3,4-tetrahydro-pyrido[2,3-d]pyrimidine-6-carboxylic acid amide
• CAS NO: 123506-55-8
• Molecular Weight: 311.3
• Mol File: 123506-55-8.mol
• Article Data: 2

Chemical Properties

• CAS DataBase Reference: 7-Amino-3-methyl-2,4-dioxo-5-phenyl-1,2,3,4-tetrahydro-pyrido[2,3-d]pyrimidine-6-carboxylic acid amide(CAS DataBase Reference)
• NIST Chemistry Reference: 7-Amino-3-methyl-2,4-dioxo-5-phenyl-1,2,3,4-tetrahydro-pyrido[2,3-d]pyrimidine-6-carboxylic acid amide(123506-55-8)
• EPA Substance Registry System: 7-Amino-3-methyl-2,4-dioxo-5-phenyl-1,2,3,4-tetrahydro-pyrido[2,3-d]pyrimidine-6-carboxylic acid amide(123506-55-8)

Safety Data

• Hazardous Substances Data: 123506-55-8(Hazardous Substances Data)

Upstream product

• 21236-97-5 3-methyl-6-aminouracil 
• 148238-27-1 (Z)-2-cyano-3-phenylacrylamide 
• 709-79-5 2-cyano-3-phenylacrylamide 
• 123506-39-8 6-hydroxyamino-3-methyluracil 

Relevant articles and documents

Studies on Uracils. 10. A Facile One-Pot Synthesis of Pyrido- and Pyrazolopyrimidines

The reaction of functionalised uracils bearing amino and hydroxyamino groups at C-6 position (4 and 5) with strongly electrophilic cyano olefins (1,2 and 3) gave rise to pyridopyrimidines 7-9 in excellent yields.Hydrazine-substituted uracil 6 gave access to an efficient one-step synthesis of pyrazolopyrimidines 10.The capture of an eliminated hydrogen molecule by cyano olefins in the case of their reaction with 4 and 6 was confirmed by the isolation of dihydrocyano olefins.This fact further supported the plausible mechanism for the formation of compounds 7-10 via dihydropyrido- and dihydropyrazolopyrimidine intermediates A and C.