123530-67-6

Basic information

• Product Name: 2-Propenoicacid,3-(2-benzothiazolyl)-,(E)-(9CI)
• Synonyms: 2-Propenoicacid,3-(2-benzothiazolyl)-,(E)-(9CI);(2E)-3-(1,3-benzothiazol-2-yl)acrylic acid(SALTDATA: FREE);(2E)-3-(1,3-benzothiazol-2-yl)acrylic acid;3-(benzo[d]thiazol-2-yl)acrylic acid
• CAS NO: 123530-67-6
• Molecular Formula: C₁₀H₇NO₂S
• Molecular Weight: 205.23
• Product Categories: BENZOTHIAZOLE
• Mol File: 123530-67-6.mol
• Article Data: 3

Chemical Properties

• Boiling Point: 410.3°C at 760 mmHg
• Flash Point: 202°C
• Appearance: /
• Density: 1.446g/cm³
• Vapor Pressure: 1.81E-07mmHg at 25°C
• Refractive Index: 1.754
• CAS DataBase Reference: 2-Propenoicacid,3-(2-benzothiazolyl)-,(E)-(9CI)(CAS DataBase Reference)
• NIST Chemistry Reference: 2-Propenoicacid,3-(2-benzothiazolyl)-,(E)-(9CI)(123530-67-6)
• EPA Substance Registry System: 2-Propenoicacid,3-(2-benzothiazolyl)-,(E)-(9CI)(123530-67-6)

Safety Data

• WGK Germany: 3
• Hazardous Substances Data: 123530-67-6(Hazardous Substances Data)

Usage

General Description

2-Propenoic acid, 3-(2-benzothiazolyl)-, (E)-(9CI) is a chemical compound with the molecular formula C13H9NOS. It exists as a clear, colorless liquid and is primarily used as an intermediate in the production of various organic compounds. It is a derivative of acrylic acid and contains a benzothiazole moiety, making it important in the synthesis of pharmaceuticals, agrochemicals, and materials science. The compound has potential applications in the field of organic synthesis and material science due to its unique structural properties and reactivity. It is important to handle this compound with caution and follow proper safety protocols when working with it.

InChI:InChI=1/C10H7NO2S/c12-10(13)6-5-9-11-7-3-1-2-4-8(7)14-9/h1-6H,(H,12,13)/b6-5+

Upstream product

• 4146-26-3 3-benzothiazol-2-yl-1,1,1-trichloro-propan-2-ol 
• 53004-62-9 methyl (E)-3-(benzo[d]thiazol-2-yl)acrylate 
• 53004-63-0 ethyl (E)-3-(benzo[d]thiazol-2-yl)acrylate 
• 53004-63-0 (E)-3-Benzothiazol-2-yl-acrylic acid ethyl ester 
• 6639-57-2 benzothiazole-2-carbaldehyde 
• 141-82-2 malonic acid 

Downstream Products

• 123530-76-7 (E)-N-<4-(4-diphenylmethyl-1-piperazinyl)butyl>-3-(2-benzothiazolyl)acrylamide 

Relevant articles and documents

CARBAMIC ACID COMPOUNDS COMPRISING A BICYCLIC HETEROARYL GROUP AS HDAC INHIBITORS

This invention pertains to certain carbamic acid compounds of the following formula, which inhibit HDAC (histone deacetylase) activity wherein: A is independently an unsubstituted or substituted bicyclic C9-10heteroaryl group (e.g., quinolinyl; quinoxalinyl; benzoxazolyl; benzothiazolyl); Q is an acid leader group, and is independently an unsubstituted or substituted, saturated or unsaturated C1 7alkylene group having a backbone length of 4 or less; with the proviso that if A is unsubstituted benzothiazol-2-yl, then Q is an unsaturated group; and with the proviso that if A is unsubstituted quinolin-6-yl, then Q is unsubstituted at the α-position; and with the proviso that A is not benzimidazol-2-yl; and pharmaceutically acceptable salts, solvates, amides, esters, ethers, chemically protected forms, and prodrugs thereof. The present invention also pertains to pharmaceutical compositions comprising such compounds, and the use of such compounds and compositions, both invitro and in vivo, to inhibit HDAC, and in the treatment of conditions mediated by HDAC, cancer, proliferative conditions, psoriasis, etc.

Acrylamide derivatives as antiallergic agents. III. Synthesis and structure-activity relationships of N-[4-(4-diphenylmethyl-1-piperazinyl)butyl]- and N-[4-(4-diphenylmethylene-1-piperidyl)butyl]-3-heteroarylacrylamides

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