123533-12-0

Basic information

• Product Name: 3'-isocyano-3'-deoxythymidine
• Synonyms: 3'-isocyano-3'-deoxythymidine
• CAS NO: 123533-12-0
• Molecular Formula: C₁₁H₁₃N₃O₄
• Molecular Weight: 0
• Mol File: 123533-12-0.mol
• Article Data: 5

Chemical Properties

• Boiling Point: °Cat760mmHg
• Flash Point: °C
• Appearance: /
• Density: g/cm³
• CAS DataBase Reference: 3'-isocyano-3'-deoxythymidine(CAS DataBase Reference)
• NIST Chemistry Reference: 3'-isocyano-3'-deoxythymidine(123533-12-0)
• EPA Substance Registry System: 3'-isocyano-3'-deoxythymidine(123533-12-0)

Safety Data

• Hazardous Substances Data: 123533-12-0(Hazardous Substances Data)

Upstream product

• 124288-70-6 5'-O-(tert-butyldimethylsilyl)-3'-deoxy-3'-isocyanothymidine 
• 132149-42-9 5'-O-Acetyl-3'-carbylamino-3'-deoxythymidine 
• 123533-10-8 5'-O-thexyldimethylsilyl-3'-formamido-3'-deoxythymidine 
• 142543-84-8 5'-O-thexyldimethylsilyl-3'-isocyano-3'-deoxythymidine 
• 123556-91-2 5'-O-thexyldimethylsilyl-3'-amino-3'-deoxythymidine 
• 123533-06-2 3'-azido-3'-deoxy-5'-O-thexyldimethylsilylthymidine 
• 124355-25-5 3'-amino-3'-deoxy-5'-O-triphenylmethyl-β-D-thymidine 
• 126441-73-4 3'-formamido-3'-deoxy-5'-formylthymidine 
• 52450-18-7 3'-amino-3'-deoxythymidine 
• 29706-84-1 1-(3-azido-2,3-deoxy-5-O-trityl-β-D-erythro-pentofuranosyl)thymine 
• 123533-05-1 5'-O-(thexyldimethylsilyl)anhydrothymidine 
• 123533-02-8 5'-O-[dimethyl(1,1,2-trimethylpropyl)silyl]thymidine 
• 123533-04-0 Methanesulfonic acid (2R,3S,5R)-2-[dimethyl-(1,1,2-trimethyl-propyl)-silanyloxymethyl]-5-(5-methyl-2,4-dioxo-3,4-dihydro-2H-pyrimidin-1-yl)-tetrahydro-furan-3-yl ester 
• 50-89-5 thymidine 

Downstream Products

• 133446-11-4 cis-chloro(3'-isocyan-3'-desoxythymidine)bis(triphenylphosphane)platinum(II)-tetrafluoroborate 

Relevant articles and documents

Synthesis and evaluation of new 2',3'-dideoxynucleoside analogs as potential anti-AIDS and anti-herpes drugs

Based on the known structure-activity relationships for the active anti-HIV, a series of 3'-deoxy-3'-N-functionalized thymidine analogs has been synthesized from thymidine. Evaluation for inhibitory activity against human immunodeficiency virus (HIV) replication in CEM cells and against herpes simplex virus in MRC-5 cells is reported.

Synthesis of N-substitued 3'-amino-3'-deoxythymidines and their biological evaluation against HIV

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Synthesis of 3'-isocyano-3'-deoxythymidine

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