123534-29-2Relevant articles and documents
Benzo [c] isoxazole -3 (1H)-one synthesis method
-
, (2016/11/24)
The invention discloses a synthesis method of benzo [c] isoxazole-3(1H)-ketone, which comprises the steps: allowing a compound shown as Formula (II) and a compound shown as a Formula (III) to perform condensation reaction to generate a compound shown as Formula (IV), oxidizing the compound shown as Formula (IV) with an oxidant in an organic solvent environment, and obtaining the benzo [c] isoxazole-3(1H)-ketone compound shown as Formula (I), wherein the oxidant is a high-valence organic iodine reagent. The method has the advantages of simple reaction course, short preparation paths of reaction raw materials, easiness in operation and the like.