1235527-98-6

Basic information

• Product Name: 3-(5,6-dihydro-4H-1,3-oxazine-2-yl)benzonitrile
• Synonyms: 3-(5,6-dihydro-4H-1,3-oxazine-2-yl)benzonitrile
• CAS NO: 1235527-98-6
• Molecular Weight: 186.213
• Mol File: 1235527-98-6.mol
• Article Data: 5

Chemical Properties

• CAS DataBase Reference: 3-(5,6-dihydro-4H-1,3-oxazine-2-yl)benzonitrile(CAS DataBase Reference)
• NIST Chemistry Reference: 3-(5,6-dihydro-4H-1,3-oxazine-2-yl)benzonitrile(1235527-98-6)
• EPA Substance Registry System: 3-(5,6-dihydro-4H-1,3-oxazine-2-yl)benzonitrile(1235527-98-6)

Safety Data

• Hazardous Substances Data: 1235527-98-6(Hazardous Substances Data)

Upstream product

• 626-17-5 benzene-1,3-dicarbonitrile 
• 156-87-6 propan-1-ol-3-amine 

Relevant articles and documents

A 2 - substituted oxazoline or 2 - substituted piperazine synthetic method (by machine translation)

The invention discloses a method for synthesizing 2 - substituted oxazoline or 2 - substituted oxazine new method, by nitrile and amino ethanol or 3 - amino - 1 - propanol as raw material, in the absence of solvent, can be used for the recycling of the sulfur to induce synthesis of 2 - substituted oxazoline and 2 - substituted piperazine. The method of the invention has low cost, simple reaction process, mild reaction conditions, the reaction time is short, the yield and the like, is suitable for the industrial generation. (by machine translation)

A green and selective synthesis of 2-aryloxazines and 2- aryltetrahydropyrimidines

An efficient method for the selective synthesis of 2-substituted oxazines and tetrahydropyrimidines by the reaction of arylnitriles with 3-amino-1-propanol and 1,3-diaminopropane in the presence of montmorillonite K-10 and KSF as inexpensive, environmenta

Ultrasound promoted selective synthesis of 2-aryl-5,6-dihydro-4H-1,3-oxazines catalyzed by K-10 and KSF montmorillonite clays: A practical procedure under mild and solvent-free conditions

Montmorillonite K-10 and KSF were found to be highly efficient, environmentally friendly and recyclable heterogeneous catalysts for the selective synthesis of a variety of 2-aryl-5,6-dihydro-4H-1,3-oxazines from arylnitriles and 3-amino-1-propanol under ultrasound irradiation. This new methodology provides excellent yields in short reaction times (10-25 min). The reaction work-up is very simple and the catalysts can be easily separated from the reaction mixture and reused several times in subsequent reactions. This catalytic system also exhibits excellent chemoselectivity in the synthesis of mono-oxazines from dinitriles.