1235545-49-9

Basic information

• Product Name: tert-butyl 9H-fluoren-9-ylmethyl [(1S,2R)-3,3-difluorocyclohexane-1,2-diyl]biscarbamate
• Synonyms: tert-butyl 9H-fluoren-9-ylmethyl [(1S,2R)-3,3-difluorocyclohexane-1,2-diyl]biscarbamate
• CAS NO: 1235545-49-9
• Molecular Weight: 472.532
• Mol File: 1235545-49-9.mol
• Article Data: 2

Chemical Properties

• CAS DataBase Reference: tert-butyl 9H-fluoren-9-ylmethyl [(1S,2R)-3,3-difluorocyclohexane-1,2-diyl]biscarbamate(CAS DataBase Reference)
• NIST Chemistry Reference: tert-butyl 9H-fluoren-9-ylmethyl [(1S,2R)-3,3-difluorocyclohexane-1,2-diyl]biscarbamate(1235545-49-9)
• EPA Substance Registry System: tert-butyl 9H-fluoren-9-ylmethyl [(1S,2R)-3,3-difluorocyclohexane-1,2-diyl]biscarbamate(1235545-49-9)

Safety Data

• Hazardous Substances Data: 1235545-49-9(Hazardous Substances Data)

Upstream product

• 1109284-47-0 tert-butyl [(1R,6S)-6-amino-2,2-difluorocyclohexyl]carbamate 
• 28920-43-6 (fluorenylmethoxy)carbonyl chloride 

Downstream Products

• 1235545-48-8 (1R,6S)-6-{[(9H-fluoren-9-ylmethoxy)carbonyl]amino}-2,2-difluorocyclohexanaminium chloride 
• 1314893-30-5 N-[(1R,6S)-6-amino-2,2-difluorocyclohexyl]-4-(6-chloropyrazolo[1,5-a]pyrimidin-3-yl)-5-ethylthiophene-2-carboxamide 
• 1314893-34-9 N-[(1R,6S)-6-amino-2,2-difluorocyclohexyl]-5-ethyl-4-(6-(trifluoromethyl)pyrazolo[1,5-a]pyrimidin-3-yl)thiophene-2-carboxamide 

Relevant articles and documents

PYRAZOLO[1,5-A]PYRIMIDINES AS MARK INHIBITORS

The invention encompasses pyrazolo[1,5-a]pyrimidine derivatives which selectively inhibit microtubule affinity regulating kinase (MARK) and are therefore useful for the treatment or prevention of Alzheimer's disease. Pharmaceutical compositions and methods of use are also included.