1235721-67-1

Basic information

• Product Name: (+)-(R)-5-[(S)-hydroxy(4-methoxyphenyl)methyl]furan-2(5H)-one
• Synonyms: (+)-(R)-5-[(S)-hydroxy(4-methoxyphenyl)methyl]furan-2(5H)-one
• CAS NO: 1235721-67-1
• Molecular Weight: 220.225
• Mol File: 1235721-67-1.mol
• Article Data: 6

Chemical Properties

• CAS DataBase Reference: (+)-(R)-5-[(S)-hydroxy(4-methoxyphenyl)methyl]furan-2(5H)-one(CAS DataBase Reference)
• NIST Chemistry Reference: (+)-(R)-5-[(S)-hydroxy(4-methoxyphenyl)methyl]furan-2(5H)-one(1235721-67-1)
• EPA Substance Registry System: (+)-(R)-5-[(S)-hydroxy(4-methoxyphenyl)methyl]furan-2(5H)-one(1235721-67-1)

Safety Data

• Hazardous Substances Data: 1235721-67-1(Hazardous Substances Data)

Upstream product

• 497-23-4 2-buten-4-olide 
• 123-11-5 4-methoxy-benzaldehyde 
• 171201-21-1 (furan-2-yloxy)triisopropylsilane 
• 121896-38-6 2-tert-butyldimethylsilyloxyfuran 
• 61550-02-5 (furan-2-yloxy)-trimethylsilane 

Relevant articles and documents

Squaramide-Sulfonamide Organocatalyst for Asymmetric Direct Vinylogous Aldol Reactions

Asymmetric direct vinylogous aldol reactions of furan-2(5H)-one with aldehydes in the presence of a catalytic amount of novel squaramide-sulfonamide organocatalyst resulted in the corresponding addition products with high to excellent enantioselectivities. This is the first successful report illustrating an example of highly stereoselective reactions using a squaramide-sulfonamide organocatalyst.

Organocatalytic asymmetric direct vinylogous aldol reactions of γ-crotonolactone with aromatic aldehydes

The direct aldol reaction of γ-crotonolactone and various aromatic aldehydes is catalyzed by bifunctional aminothiourea and aminosquaramide organocatalysts to provide diastereomerically and enantiomerically enriched 5-substituted 2(5H) furanones (γ-buteno

Asymmetric direct vinylogous aldol reaction of unactivated γ-butenolide to aldehydes

(Figure presented) The asymmetric direct vinylogous aldol reaction of unactivated γ-butenolide with aldehydes has been developed, giving the corresponding 5-(1′-hydroxy)butenolide derivatives in high yields (up to 93%) and enantioselectivities (up to 83%