1235974-13-6Relevant articles and documents
Anti-neuroinflammatory activity of 1,5-benzodiazepine derivatives
Ha, Sang Keun,Shobha, Donthabhaktuni,Moon, Eunjung,Chari, Murugulla A.,Mukkanti, Kagga,Kim, Sung-Hoon,Ahn, Kwang-Hyun,Kim, Sun Yeou
, p. 3969 - 3971 (2010)
A series of 2,3-dihydro-1,5-benzodiazepines were synthesized and evaluated for anti-inflammatory effects in microglia cells. Among the 1,5-benzodiazepines tested, compound 3e strongly inhibited LPS-induced nitric oxide (NO) production, with an IC50/