1235992-72-9Relevant articles and documents
Synthesis and in vivo evaluation of phenethylpiperazine amides: Selective 5-hydroxytryptamine2A receptor antagonists for the treatment of insomnia
Xiong, Yifeng,Ullman, Brett,Choi, Jin-Sun Karoline,Cherrier, Martin,Strah-Pleynet, Sonja,Decaire, Marc,Dosa, Peter I.,Feichtinger, Konrad,Teegarden, Bradley R.,Frazer, John M.,Yoon, Woo H.,Shan, Yun,Whelan, Kevin,Hauser, Erin K.,Grottick, Andrew J.,Semple, Graeme,Al-Shamma, Hussien
experimental part, p. 5696 - 5706 (2010/10/18)
Recent developments in sleep research suggest that antagonism of the serotonin 5-HT2A receptor may improve sleep maintenance insomnia. We herein report the discovery of a series of potent and selective serotonin 5-HT2A receptor antag