1236045-07-0Relevant articles and documents
Cationic Pd(II)-catalyzed tandem reaction of 2-arylethynylanilines and aldehydes: An efficient synthesis of substituted 3-hydroxymethyl indoles
Han, Xiuling,Lu, Xiyan
supporting information; experimental part, p. 3336 - 3339 (2010/10/21)
(Equation Presented). An efficient cationic palladium(II)-catalyzed synthesis of substituted 3-hydroxymethylindoles from readily accessible starting materials is developed. This tandem reaction involves an intramolecular aminopalladation of an alkyne and an addition to the carbonyl group to quench the carbon-palladium bond to complete the catalytic cycle without the necessity of a redox system.