1236145-37-1

Basic information

• Product Name: 2-chloro-12H-chromeno[2',3':4,5]imidazo[1,2-a]pyridine
• CAS NO: 1236145-37-1
• Molecular Weight: 256.691
• Mol File: 1236145-37-1.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: 2-chloro-12H-chromeno[2',3':4,5]imidazo[1,2-a]pyridine(CAS DataBase Reference)
• NIST Chemistry Reference: 2-chloro-12H-chromeno[2',3':4,5]imidazo[1,2-a]pyridine(1236145-37-1)
• EPA Substance Registry System: 2-chloro-12H-chromeno[2',3':4,5]imidazo[1,2-a]pyridine(1236145-37-1)

Safety Data

• Hazardous Substances Data: 1236145-37-1(Hazardous Substances Data)

Upstream product

• 17281-59-3 2-pyridin-1-ium-1-ylacetonitrile chloride 
• 635-93-8 5-chlorosalicyclaldehyde 

Relevant articles and documents

One-pot approach to the synthesis of novel 12H-chromeno[2′,3′:4,5]imidazo[1,2-a]pyridines in aqueous media

The chromeno-imidazo[1,2-a]pyridine scaffold was generated in an one pot condensation/cyclization reaction involving a salicylaldehyde and 1-(cyanomethyl)pyridinium chloride, in aqueous sodium carbonate solution. These novel compounds were isolated in 47-71% yield. The reaction pathway was followed by 1H NMR spectroscopy allowing a clear understanding of the side reactions involved in the process. Different mono-substituted pyridinium chlorides were synthesized and reacted with mono-substituted salicylaldehydes and a detailed discussion of the scope of the synthetic method is also presented.