1237261-65-2 Usage
Description
(1S,2R)-2-((1,3-dioxoisoindolin-2-yl)Methyl)-N,N-diethyl-1-phenylcyclopropanecarboxamide is a complex organic chemical compound characterized by a cyclopropane ring fused with a phenyl group. It is adorned with a diethyl substituent and a carboxamide functional group, which may contribute to its reactivity and potential applications. Notably, the presence of an isoindolin-1,3-dione moiety, known for its biological activity, suggests that this compound could be of interest in the fields of medicinal chemistry and pharmaceutical research.
Uses
Used in Medicinal Chemistry:
(1S,2R)-2-((1,3-dioxoisoindolin-2-yl)Methyl)-N,N-diethyl-1-phenylcyclopropanecarboxamide is used as a building block or intermediate in the synthesis of pharmaceuticals due to its unique structural features and the biological activity associated with the isoindolin-1,3-dione moiety.
Used in Pharmaceutical Research:
In pharmaceutical research, this compound may serve as a template for the development of new drugs, given its potential to interact with biological targets due to its diverse functional groups and the presence of the bioactive isoindolin-1,3-dione core.
Used in Drug Design and Optimization:
(1S,2R)-2-((1,3-dioxoisoindolin-2-yl)Methyl)-N,N-diethyl-1-phenylcyclopropanecarboxamide can be utilized in the design and optimization of drugs targeting specific diseases, leveraging its structural diversity and the possibility of modifying its substituents to improve binding affinity and selectivity.
Used in Chemical Synthesis:
As a versatile chemical intermediate, (1S,2R)-2-((1,3-dioxoisoindolin-2-yl)Methyl)-N,N-diethyl-1-phenylcyclopropanecarboxamide may be employed in various chemical synthesis processes to produce a range of compounds with potential applications in different industries, including but not limited to pharmaceuticals, agrochemicals, and materials science.
Check Digit Verification of cas no
The CAS Registry Mumber 1237261-65-2 includes 10 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 7 digits, 1,2,3,7,2,6 and 1 respectively; the second part has 2 digits, 6 and 5 respectively.
Calculate Digit Verification of CAS Registry Number 1237261-65:
(9*1)+(8*2)+(7*3)+(6*7)+(5*2)+(4*6)+(3*1)+(2*6)+(1*5)=142
142 % 10 = 2
So 1237261-65-2 is a valid CAS Registry Number.
1237261-65-2Relevant articles and documents
Preparation method of levomilnacipran key intermediate
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Paragraph 0014, (2020/07/13)
Levomilnacipran has a chemical name of (1R,2S)-2-(aminomethyl)-N,N-diethyl-1-phenylcyclopropanecarboxamide, is a medicine which is researched and developed by a French PierreFabre laboratory at the earliest time and is used for treating adult severe depre
Chiral Bidentate Boryl Ligand Enabled Iridium-Catalyzed Enantioselective C(sp3)-H Borylation of Cyclopropanes
Shi, Yongjia,Gao, Qian,Xu, Senmiao
, p. 10599 - 10604 (2019/08/28)
We herein report an Ir-catalyzed enantioselective C(sp3)-H borylation of cyclopropanecarboxamides using a chiral bidentate boryl ligand for the first time. A variety of substrates with α-quaternary carbon centers could be compatible in this reaction to provide β-borylated products with good to excellent enantioselectivities. We have also demonstrated that the borylated products can be used as versatile precursors engaging in stereospecific transformations of C-B bonds, including the synthesis of a bioactive compound Levomilnacipran.
Preparation method of levomilnacipran hydrochloride
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, (2017/04/19)
The invention provides a preparation method of levomilnacipran hydrochloride. According to the preparation method, a mixed liquid is obtained through a mixed reaction of a compound adopting the structure shown in the formula (II) and alkali; then acid is
