123731-68-0

Basic information

• Product Name: (S)-1,2-EPOXYPENTANE
• Synonyms: (S)-1,2-EPOXYPENTANE;Oxirane, 2-propyl-,(2S)-;(S)-2-Propyloxirane
• CAS NO: 123731-68-0
• Molecular Formula: C₅H₁₀O
• Molecular Weight: 86.13
• Mol File: 123731-68-0.mol
• Article Data: 15

Chemical Properties

• Appearance: /
• CAS DataBase Reference: (S)-1,2-EPOXYPENTANE(CAS DataBase Reference)
• NIST Chemistry Reference: (S)-1,2-EPOXYPENTANE(123731-68-0)
• EPA Substance Registry System: (S)-1,2-EPOXYPENTANE(123731-68-0)

Safety Data

• Hazardous Substances Data: 123731-68-0(Hazardous Substances Data)

Usage

General Description

(S)-1,2-EPOXYPENTANE, also known as (S)-3-ethyl-1,2-epoxypropane, is a chemical compound with the molecular formula C5H10O. It is an epoxide, which is a type of organic compound with a three-membered ring containing one oxygen atom. (S)-1,2-EPOXYPENTANE is a colorless liquid at room temperature and is highly flammable. (S)-1,2-EPOXYPENTANE is primarily used as an intermediate in the production of other chemicals, including pharmaceuticals, pesticides, and plastics. It is also used as a solvent and as a reagent in organic synthesis. (S)-1,2-EPOXYPENTANE can be hazardous if inhaled or ingested, and appropriate safety measures should be taken when handling this compound.

Upstream product

• 29117-54-2 (S)-(-)-1,2-pentanediol 
• 1003-14-1 2-pentyloxirane 
• 139365-00-7 (2R)-2-chloropentan-1-ol 
• 109-67-1 1-penten 
• 141339-40-4 S-1-chloromethyl-1-butanol 
• 2013-12-9 D-norvaline 
• 6155-96-0 (2R)-2-Chloropentanoic acid 
• 6600-40-4 L-Norvaline 
• 41014-93-1 2-(S)-hydroxyvaleric acid 

Downstream Products

• 87887-12-5 (-)-(2S)-1-{[(1S,6R)-2,2,6-trimethylcyclohexyl]oxy}pentan-2-ol 
• 87887-12-5 (+)-(2S)-1-{[(1R,6S)-2,2,6-trimethylcyclohexyl]oxy}pentan-2-ol 
• 265094-58-4 (S)-1-Benzenesulfonyl-1-((1S,6R)-2,2,6-trimethyl-cyclohexyl)-hexan-3-ol 
• 265094-56-2 (S)-1-Benzenesulfonyl-1-((1R,6S)-2,2,6-trimethyl-cyclohexyl)-hexan-3-ol 
• 929682-56-4 2-(4-methoxy-phenyl)-6-[2,2,4-trimethyl-6-(1-propyl-but-3-enyloxy)-tetrahydro-[1,3]dioxolo[4,5-c]pyran-7-yloxy]-hexahydro-pyrano[3,2-d][1,3]dioxine-7,8-diol 
• 929682-81-5 acetic acid 8-acetoxy-2-(4-methoxy-phenyl)-6-[2,2,4-trimethyl-6-(1-propyl-but-3-enyloxy)-tetrahydro-[1,3]dioxolo[4,5-c]pyran-7-yloxy]-hexahydro-pyrano[3,2-d][1,3]dioxin-7-yl ester 
• 929682-57-5 2-methyl-but-2-enoic acid 7-hydroxy-2-(4-methoxy-phenyl)-6-[2,2,4-trimethyl-6-(1-propyl-but-3-enyloxy)-tetrahydro-[1,3]dioxolo[4,5-c]pyran-7-yloxy]-hexahydro-pyrano[3,2-d][1,3]dioxin-8-yl ester 
• 929682-58-6 2-methyl-but-2-enoic acid 7-(tert-butyl-dimethyl-silanyloxy)-2-(4-methoxy-phenyl)-6-[2,2,4-trimethyl-6-(1-propyl-but-3-enyloxy)-tetrahydro-[1,3]dioxolo[4,5-c]pyran-7-yloxy]-hexahydro-pyrano[3,2-d][1,3]dioxin-8-yl ester 
• 929682-75-7 C₅₉H₈₆O₁₆Si₂ 
• 929682-73-5 C₆₁H₈₈O₁₆Si₂ 
• 253454-07-8 (1'S,3S,6'S)-1-(2,2,6-trimethylcyclohexyl)hex-1-en-3-ol 
• 253454-10-3 (+)-(1'R,3S,6'S)-1-(2,2,6-trimethylcyclohexyl)hexan-3-ol 
• 70788-30-6 (-)-(1'S,3S,6'R)-1-(2,2,6-trimethylcyclohexyl)hexan-3-ol 
• 269409-64-5 (S)-2-((2R,6S)-4,4-Dioxo-7a-phenylsulfanyl-6-propyl-hexahydro-1,5-dioxa-4λ⁶-thia-inden-2-yl)-propionic acid methyl ester 

Relevant articles and documents

Long-range stereo-relay: Relative and absolute configuration of 1,n-glycols from circular dichroism of liposomal porphyrin esters

The relative and absolute configurations of long-chain syn- and anti-1,5-, 1,7- and 1,9-glycols were determined from exciton-coupled circular dichroism (ECCD) of the corresponding bis-5-(4′-carboxyl)-5,10,15,20-tetraphenylporphyrin esters measured in uniform (φ = 26 nm), unilamellar liposomes. Long-range transmission of configuration by ECCD is made possible through partial ordering of glycol ester-lipid molecules by liposomal bilayers. Copyright

A formal synthesis of porantheridine and an epimer

(Chemical Equation Presented) A formal synthesis of porantheridine and a synthesis of its C6-epimer have been completed, employing silver-catalyzed allene cyclization to form a common cis-isoxazolidine intermediate and related N-acyl iminium ion intermediates for side-chain introduction. The stereochemistry of this step can be controlled by choice of the N-protection method.

Bioproduction of chiral epoxyalkanes using styrene monooxygenase from rhodococcus sp. ST-10 (RhSMO)

We describe the enantioselective epoxidation of straight-chain aliphatic alkenes using a biocatalytic system containing styrene monooxygenase from Rhodococcus sp. ST-10 and alcohol dehydrogenase from Leifsonia sp. S749. The biocatalyzed enantiomeric epoxidation of 1-hexene to (S)-1,2-epoxyhexane (44.6 mM) using 2-propanol as the hydrogen donor was achieved under optimized conditions. The biocatalyst had broad substrate specificity for various aliphatic alkenes, including terminal, internal, unfunctionalized, and di- and tri-substituted alkenes. Here, we demonstrate that this biocatalytic system is suitable for the efficient production of enantioenriched (S)-epoxyalkanes.

Total synthesis of neopeltolide and analogs

Neopeltolide, a potent cytotoxin from a Carribean sponge, was synthesized through a brief sequence that highlights the use of ethers as oxocarbenium ion precursors. Other key steps include an acid-mediated etherification and sequence that features a Sonogashira reaction, an intramolecular alkyne hydrosilylation reaction, and a Tamao oxidation. The alkene that is required for the oxidative cyclization can be hydrogenated to provide access to the natural product or an epimer, or can be epoxidized or dihydroxylated to form polar analogs.