123736-87-8

Basic information

• Product Name: (S)-2-acetoxy-4-phenylbutanoic acid
• Synonyms: (S)-2-acetoxy-4-phenylbutanoic acid
• CAS NO: 123736-87-8
• Molecular Weight: 222.241
• Mol File: 123736-87-8.mol
• Article Data: 2

Chemical Properties

• CAS DataBase Reference: (S)-2-acetoxy-4-phenylbutanoic acid(CAS DataBase Reference)
• NIST Chemistry Reference: (S)-2-acetoxy-4-phenylbutanoic acid(123736-87-8)
• EPA Substance Registry System: (S)-2-acetoxy-4-phenylbutanoic acid(123736-87-8)

Safety Data

• Hazardous Substances Data: 123736-87-8(Hazardous Substances Data)

Upstream product

• 883723-47-5 2-acetoxy-4-phenylbutanoic acid 
• 108-05-4 vinyl acetate 
• 4263-93-8 2-hydroxy-4-phenylbutanoic acid 
• 117017-04-6 (R)-2-acetoxy-4-phenylbutanoic acid 

Downstream Products

• 115016-95-0 (S)-2-hydroxy-4-phenylbutanoic acid 

Relevant articles and documents

Enantio-complementary deracemization of (±)-2-hydroxy-4- phenylbutanoic acid and (±)-3-phenyllactic acid using lipase-catalyzed kinetic resolution combined with biocatalytic racemization

Deracemization of (±)-3-phenyllactic acid (1) and (±)-2-hydroxy-4-phenylbutanoic acid (2) was accomplished by lipase-catalysed kinetic resolution coupled to biocatalytic racemization of the non-reacting substrate enantiomers using Lactobacillus paracasei DSM 20008. Cyclic repetition of this sequence led to a single enantiomeric product from the racemate. Access to both enantiomers was achieved by switching between lipase-catalysed acyl-transfer and ester hydrolysis reactions. Both products constitute important building blocks for virus protease- and ACE-inhibitors, respectively.