12375-04-1

Basic information

• Product Name: DODECACARBONYLTETRA-MU-HYDRIDOTETRAOSMIUM
• Synonyms: DODECACARBONYLTETRA-MU-HYDRIDOTETRAOSMIUM;powder,;Dodecacarbonyltetra-m-hydridotetraOsmium;dodecacarbonyltetra-μ-hydridotetraosmium
• CAS NO: 12375-04-1
• Molecular Formula: C₁₂H₄O₁₂Os₄
• Molecular Weight: 1097.04
• Mol File: 12375-04-1.mol
• Article Data: 2

Chemical Properties

• Appearance: /
• CAS DataBase Reference: DODECACARBONYLTETRA-MU-HYDRIDOTETRAOSMIUM(CAS DataBase Reference)
• NIST Chemistry Reference: DODECACARBONYLTETRA-MU-HYDRIDOTETRAOSMIUM(12375-04-1)
• EPA Substance Registry System: DODECACARBONYLTETRA-MU-HYDRIDOTETRAOSMIUM(12375-04-1)

Safety Data

• Hazard Codes: Xi
• Statements: 36/37/38
• Safety Statements: 26-36
• WGK Germany: 3
• Hazardous Substances Data: 12375-04-1(Hazardous Substances Data)

Usage

General Description

Dodecacarbonyltetra-mu-hydridotetraosmium, also known as Os4(CO)12(H)4, is a chemical compound consisting of four osmium atoms surrounded by twelve carbonyl groups and four hydride atoms. It is a cluster compound with a cage-like structure, and it is known for its high reactivity and ability to catalyze various chemical reactions. Dodecacarbonyltetra-mu-hydridotetraosmium is commonly used as a catalyst in organic synthesis, particularly in the hydrogenation of alkenes and alkynes. It is also employed in the production of specialty chemicals and pharmaceuticals. Despite its potential applications, the compound poses significant health and environmental hazards, and its handling and use require careful consideration of safety measures.

InChI:InChI=1/12CO.4Os.4H/c12*1-2;;;;;;;;/r2C6H2O6Os2/c2*7-1-13(2-8,3-9)14(4-10,5-11)6-12/h2*13-14H

Upstream product

• 97689-39-9 HOs₃(CH₃OCCC₆H₅CC₆H₅)(CO)9 
• 76287-22-4 HOs₃(HOCCHCH)(CO)9 
• 68-12-2 N,N-dimethyl-formamide 

Relevant articles and documents

Methylidyne-alkyne coupling on triruthenium clusters and hydrogenation of cluster-bound 1,3-dimetalloallyl units. A new model for Fischer-Tropsch chain growth

Alkylidyne-alkyne coupling occurs upon reaction of H3Ru3(μ3-CX)(CO)9 (X = OMe, Me, Ph, or CH2CH2CMe3) at 25 °C or HRu3(μ-CX)(CO)10 (X = OMe) at 60 °C with alkynes R1C2R2, forming 1,3-dimetalloallyl clusters HRu3(μ3-η3-XCCRCR)(CO)9 (X = OMe, (R1, R2) = (H, H), (Me, Me), (Ph, Ph), (H, Ph), (H, CMe3), (H, n-Bu), (H, CO2Me), (Ph, CO2Me), (H, OEt); X = Ph, (R1, R2) = (Ph, Ph); X = Me, (R1, R2) = (Me, Me); X = CH2CH2CMe3, (R1, R2) = (Ph, Ph)) in yields of 15-90%. In an analogous fashion, HOs3(μ-COMe)(CO)10 and PhC2Ph yield HOs3(μ3-η3-MeOCCPhCPh)(CO)9. One equivalent of the appropriate cis-alkene is formed from reduction of alkyne by H3Ru3(μ3-CX)(CO)9. With unsymmetrical alkynes the relative amounts of the two possible regioisomers depend upon the alkyne substituents. Coupling from either H3R3(μ3-COMe)(CO)9 or HRu3(μ-COMe)(CO)10 forms HRu3(μ3-η3-MeOCCR1CR 2)(CO)9 in the relative amounts (R1, R2) = (H, Ph)/(Ph, H), 3:1, (H, n-Bu)/(n-Bu, H), 2:1, (H, CMe3,)/(CMe3, H), 20:1, (H, CO2Me)/(CO2Me, H), 2:1, (H, OEt)/(OEt, H), 1:0, (Me, C7-H15, Me), 3:1, and (CO2Me, Ph)/(Ph, CO2Me), 2:1. Hydrogenation (90 °C, 1-4 atm) of HRu3(μ3-η3MeOCCR1CR 2)(CO)9 ((R1, R2) = (H, H), (H, CMe3), (Me, Me), (Ph, Ph), (H, OEt), (H, Ph), (H, n-Bu), (n-Bu, H), (H, CO2Me)) produces in each case the corresponding H3Ru3(μ3CCHR1CH2R 2)(CO)9 in yields of 6-43%; also formed are substantial quantities of H4Ru4(CO)12. Hydrogenation of DRu3(μ3-η3-MeOCCHCCMe 3)(CO)9 produces exclusively H3Ru3(μ3-CCH2CHDCMe 3)(CO)9. This alkylidyne-alkyne coupling and subsequent hydrogenation to form an alkylidyne of longer carbon chain length suggests a mechanism to account for 2-methylated hydrocarbon products in the Fischer-Tropsch reaction.