1237791-75-1Relevant articles and documents
Reactions of 1,2,4-triazole derivatives with a Model thiirane
Klen,Khaliullin
, p. 685 - 688 (2010)
Reactions of 3-mono- and 3,5-disubstituted 1,2,4-triazoles with a model thiirane, 8-bromo-1,3-dimethyl-7-(thiiran-2-ylmethyl)-3,7- dihydro-1H-purine-2,6-diones proceed at the positions N1 and N 2 of the triazole ring and yield 7-(5-R-3-R′-1,2,4-triazol-1- yl)methyl- and/or 7-(5-R′-3-R-1,2,4-triazol-1-yl)methyl-1,3-dimethyl-6,7- dihydro[1,3]thiazolo[2,3-f]-purine-2,4-(1H,3H)-diones. 3-Methylsulfonyl-1,2,4- triazole reacted regiospecifically at the position N1 forming 1,3-dimethyl-7-[(3-methyl-sulfonyl-1,2,4-triazole-1-yl)-methyl]-6,7-dihydro[1,3] thiazolo-[2,3-f]purine-2,4(1H,3H)-dione. Pleiades Publishing, Ltd., 2010.