123812-77-1 Usage
Functional groups
Two carboxylic acid functional groups
Type of compound
Fluorinated derivative of cyclobutanedicarboxylic acid
Applications
a. Organic synthesis
b. Pharmaceutical research
c. Building block for complex molecule synthesis
d. Development of pharmaceutical drugs or agrochemicals
e. Precursor for fluorinated polymers and materials with unique properties
Structure
Cyclobutane ring with two carboxylic acid groups and a fluorine atom at the 3-position
Physical state
Likely a solid, based on its molecular weight and structure
Solubility
Likely soluble in polar solvents such as water or methanol, due to the presence of carboxylic acid groups
Stability
Stable under normal conditions, but may be sensitive to heat or strong bases due to the presence of carboxylic acid groups
Reactivity
Reactive towards nucleophiles and other reagents that can react with carboxylic acid groups, as well as electrophilic reagents that can react with the fluorine atom.
Check Digit Verification of cas no
The CAS Registry Mumber 123812-77-1 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 1,2,3,8,1 and 2 respectively; the second part has 2 digits, 7 and 7 respectively.
Calculate Digit Verification of CAS Registry Number 123812-77:
(8*1)+(7*2)+(6*3)+(5*8)+(4*1)+(3*2)+(2*7)+(1*7)=111
111 % 10 = 1
So 123812-77-1 is a valid CAS Registry Number.
123812-77-1Relevant articles and documents
Kinetic and thermodynamic effects in the thermal electrocyclic ring-openings of 3-fluorocyclobutene, 3,3-difluorocyclobutene, and 3-(trifluoromethyl)cyclobutene
Dolbier,Gray,Keaffaber,Celewicz,Koronia k
, p. 363 - 367 (1990)
The synthesis and thermal electrocyclic ring-opening of 3-fluorocylobutane, 4, 3,3-difluorocyclobutane, 5, and 3-(trifluoromethyl)cyclobutane, 6, are reported. Activation energies for their ring-openings were found to be 28.1, 45.0, and 36.3 kcal/mol, respectively. 6 was found to form both the (E)- and the (Z)-5,5,5-trifluoro-1,3,butadienes, in a 95:5 ratio. Thermal equilibrations of the diene products from 4 and 6 were also carried out. The results demonstrate that a CF3 group exhibits only a slight preference for outward rotation (ΔE(a) = 1.2 kcal/mol), while a fluorine substituent gives rise to a much more dramatic outward rotational preference (ΔE(a) = 13.8 kcal/mol). These results were consistent with those previously reported for perfluorinated systems and with theoretical expectations.
