123839-74-7

Basic information

• Product Name: 1,4-dichloro-5-<(2,4,6-trimethylphenyl)methoxy>-9,10-anthracenedione
• Synonyms: 1,4-dichloro-5-<(2,4,6-trimethylphenyl)methoxy>-9,10-anthracenedione
• CAS NO: 123839-74-7
• Molecular Weight: 425.311
• Mol File: 123839-74-7.mol
• Article Data: 3

Chemical Properties

• CAS DataBase Reference: 1,4-dichloro-5-<(2,4,6-trimethylphenyl)methoxy>-9,10-anthracenedione(CAS DataBase Reference)
• NIST Chemistry Reference: 1,4-dichloro-5-<(2,4,6-trimethylphenyl)methoxy>-9,10-anthracenedione(123839-74-7)
• EPA Substance Registry System: 1,4-dichloro-5-<(2,4,6-trimethylphenyl)methoxy>-9,10-anthracenedione(123839-74-7)

Safety Data

• Hazardous Substances Data: 123839-74-7(Hazardous Substances Data)

Upstream product

• 6770-15-6 1,4-dichloro-5-hydroxy-9,10-anthracenedione 
• 1585-16-6 2-chloromethyl-1,3,5-trimethylbenzene 
• 3223-90-3 1,4-dichloro-5-nitro-anthraquinone 
• 3223-94-7 1-amino-5,8-dichloroanthraquinone 
• 602-25-5 1,4-dichloroanthraquinone 

Downstream Products

• 156498-26-9 5-Chloro-2-(2-hydroxy-ethyl)-7-(2,4,6-trimethyl-benzyloxy)-2H-dibenzo[cd,g]indazol-6-one 
• 156498-25-8 5-Chloro-2-(2-hydroxy-ethyl)-10-(2,4,6-trimethyl-benzyloxy)-2H-dibenzo[cd,g]indazol-6-one 
• 109921-42-8 <5-chloro-2,6-dihydro-6-oxo-7-<(2,4,6-trimethylphenyl)methoxy>anthra<1,9-cd>pyrazol-2-yl>(2-hydroxyethyl)carbamic acid, 1,1-dimethylethyl ester 
• 109921-41-7 <5-chloro-2,6-dihydro-6-oxo-10-<(2,4,6-trimethylphenyl)methoxy>anthra<1,9-cd>pyrazol-2-yl>(2-hydroxyethyl)carbamic acid, 1,1-dimethylethyl ester 
• 156498-27-0 Toluene-4-sulfonic acid 2-[5-chloro-6-oxo-7-(2,4,6-trimethyl-benzyloxy)-6H-dibenzo[cd,g]indazol-2-yl]-ethyl ester 
• 88303-61-1 losoxantrone 
• 123839-76-9 2-<2-<(2-hydroxyethyl)amino>ethyl>-5-<<2-<(2-hydroxyethyl)amino>ethyl>amino>-7-<(2,4,6-trimethylphenyl)methoxy>anthra<1,9-cd>pyrazol-6(2H)-one 
• 88303-60-0 7-hydroxy-2-{2-[(2-hydroxyethyl)amino]ethyl}-5-({2-[(2-hydroxyethyl)amino]ethyl}amino)anthra(1,9-cd)pyrazol-6(2H)-one 

Relevant articles and documents

Reversal of the regioselectivity of anthrapyrazole formation. A new synthesis of Losoxantrone (DUP941)

Losoxantrone, a potent anticancer agent, has been efficiently synthesized in a 6 step process from 5-hydroxy-1,4- dichloroanthracene-9,10-dione.

Process for preparing substituted anthra[1,9-cd]pyrazol-6(2H)-ones

An improved process for producing anthra[1,9-cd]-pyrazol-6(2H)-ones from 1,4-dichloro-5,8-disubstituted 9,10-anthracenediones. The process produces higher yields by using a new combination of protecting groups on the compounds which allows for easier and cleaner chromatographic resolution. The compounds produced have antibacterial, antifungal, antileukemic, and antitumor activity.