1238840-23-7Relevant articles and documents
Photodecarboxylative additions of N-protected α-amino acids to N-methylphthalimide
Gallagher, Sonia,Hatoum, Fadi,Zientek, Nicolai,Oelgem?ller, Michael
, p. 3639 - 3641 (2010)
Photoreactions involving N,N-dimethylated α-amino acid salts and N-methylphthalimide are dominated by photoreduction and acetone trapping. Only, N-phenyl glycinate underwent photodecarboxylative addition in a moderate yield of 30%. In contrast, N-acylated α-amino acid salts readily gave addition products in fair to high yields of 20-95%. Comparison experiments with N,N-dimethylacetamide and amino-/amido-containing phthalimides revealed the origin of the crucial electron-transfer step and the reactivity order NR 3 RCO2- ≥ RCONR2 was established.