1239028-26-2

Basic information

• Product Name: methyl 2-hydroxy-5-[4-(3,5-dimethoxyphenyl)-1H-1,2,3-triazol-1-yl]benzoate
• Synonyms: methyl 2-hydroxy-5-[4-(3,5-dimethoxyphenyl)-1H-1,2,3-triazol-1-yl]benzoate
• CAS NO: 1239028-26-2
• Molecular Weight: 355.35
• Mol File: 1239028-26-2.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: methyl 2-hydroxy-5-[4-(3,5-dimethoxyphenyl)-1H-1,2,3-triazol-1-yl]benzoate(CAS DataBase Reference)
• NIST Chemistry Reference: methyl 2-hydroxy-5-[4-(3,5-dimethoxyphenyl)-1H-1,2,3-triazol-1-yl]benzoate(1239028-26-2)
• EPA Substance Registry System: methyl 2-hydroxy-5-[4-(3,5-dimethoxyphenyl)-1H-1,2,3-triazol-1-yl]benzoate(1239028-26-2)

Safety Data

• Hazardous Substances Data: 1239028-26-2(Hazardous Substances Data)

Upstream product

• 1239028-02-4 methyl 5-azido-2-hydroxybenzoate 
• 171290-52-1 1-Ethynyl-3,5-dimethoxy-benzene 

Downstream Products

• 1239028-30-8 2-hydroxy-5-[4-(3,5-dimethoxyphenyl)-1H-1,2,3-triazol-1-yl]benzoic acid 

Relevant articles and documents

A rapid synthesis of lavendustin-mimetic small molecules by click fragment assembly

Lavendustin-mimetic small molecules modifying the linker -CH 2-NH- with an 1,2,3-triazole ring have been synthesized via a click chemistry. Two pharmacophoric fragments of lavendustin were varied to investigate chemical space and the auxophoric -CH2-NH- was altered to an 1,2,3-triazole for rapid click conjugation. The small molecules were evaluated against HCT116 colon cancer and CCRF-CEM leukemia cell lines. Among 28 analogues, 3-phenylpropyl ester 26b inhibited CCRF-CEM leukemia cell growth with GI50 value of 0.9 μM.