1239420-88-2Relevant articles and documents
Synthesis and antimicrobial activities of some novel 4-substituted pyrazoline derivatives
Godhasra,Patel,Kansagara,Thanki,Shah
experimental part, p. 495 - 499 (2011/07/31)
A series of 5-aryl-3-isopropyl-4-[N-phenyl-aminocarbonyl]-4,5-dihydro-1H- pyrazoles were synthesized by the reaction between 3-aryl-2-isobutanoyl-N- phenyl-acrylamide with hydrazine hydrate in acetic acid as solvent gives acetyl pyrazoline. All the compounds have been evaluated for their in vitro biological assay like antibacterial activity towards Gram-positive and Gram-negative bacterial strains and antifungal activity towards Aspergillus niger at a concentration of 40 μg. The biological activities of synthesized compounds were compared with standard drugs.