1239610-44-6 Usage
General Description
HDAC-IN-1 is a chemical compound that has been identified as a potential histone deacetylase inhibitor, which means it has the ability to regulate gene expression by affecting the acetylation of histone proteins. HDAC-IN-1 has shown potential in preclinical studies for its ability to inhibit the activity of histone deacetylase enzymes, which are involved in epigenetic regulation and play a role in various diseases, including cancer. HDAC-IN-1 is being investigated for its potential as a therapeutic agent for the treatment of cancer and other diseases where histone deacetylase inhibition could be beneficial. Its mechanism of action and potential therapeutic applications make it an important compound in the field of epigenetics and cancer research.
Check Digit Verification of cas no
The CAS Registry Mumber 1239610-44-6 includes 10 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 7 digits, 1,2,3,9,6,1 and 0 respectively; the second part has 2 digits, 4 and 4 respectively.
Calculate Digit Verification of CAS Registry Number 1239610-44:
(9*1)+(8*2)+(7*3)+(6*9)+(5*6)+(4*1)+(3*0)+(2*4)+(1*4)=146
146 % 10 = 6
So 1239610-44-6 is a valid CAS Registry Number.
1239610-44-6Relevant articles and documents
Class II (IIa)-selective histone deacetylase inhibitors. 1. Synthesis and biological evaluation of novel (aryloxopropenyl)pyrrolyl hydroxyamides
Mai, Antonello,Massa, Silvio,Pezzi, Riccardo,Simeoni, Silvia,Rotili, Dante,Nebbioso, Angela,Scognamiglio, Annamaria,Altucci, Lucia,Loidl, Peter,Brosch, Gerald
, p. 3344 - 3353 (2007/10/03)
Chemical manipulations performed on aroyl-pyrrolyl-hydroxyamides (APHAs) led to (aryloxopropenyl)pyrrolyl hydroxamates 2a-w, and their inhibition against maize HDACs and their class I or class II HDAC selectivity were determined. In particular, from these
