1239713-09-7

Basic information

• Product Name: N-[2-(4-chlorophenyl)-2-hydroxyethyl]benzo[b]furan-2-carboxamide
• CAS NO: 1239713-09-7
• Molecular Weight: 315.756
• Mol File: 1239713-09-7.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: N-[2-(4-chlorophenyl)-2-hydroxyethyl]benzo[b]furan-2-carboxamide(CAS DataBase Reference)
• NIST Chemistry Reference: N-[2-(4-chlorophenyl)-2-hydroxyethyl]benzo[b]furan-2-carboxamide(1239713-09-7)
• EPA Substance Registry System: N-[2-(4-chlorophenyl)-2-hydroxyethyl]benzo[b]furan-2-carboxamide(1239713-09-7)

Safety Data

• Hazardous Substances Data: 1239713-09-7(Hazardous Substances Data)

Upstream product

• 41870-82-0 2-amino-1-(4-chlorophenyl)ethanol 

Relevant articles and documents

Synthesis and CYP24A1 inhibitory activity of N-(2-(1H-imidazol-1-yl)-2- phenylethyl)arylamides

A series of N-(2-(1H-imidazol-1-yl)-2-phenylethyl)arylamides were prepared, using an efficient three- to five-step synthesis, and evaluated for their inhibitory activity against human cytochrome P450C24A1 (CYP24A1) hydroxylase. Inhibition ranged from IC50 0.3-72 μM compared with the standard ketoconazole IC50 0.52 μM, with the styryl derivative (11c) displaying enhanced activity (IC50 = 0.3 μM) compared with the standard, providing a useful preliminary lead for drug development.