1239717-00-0Relevant articles and documents
Synthesis and structure-activity relationships of N-aryl-piperidine derivatives as potent (partial) agonists for human histamine H3 receptor
Ishikawa, Makoto,Furuuchi, Takeshi,Yamauchi, Miki,Yokoyama, Fumikazu,Kakui, Nobukazu,Sato, Yasuo
experimental part, p. 5441 - 5448 (2010/09/05)
4-((1H-Imidazol-4-yl)methyl)-1-aryl-piperazine and piperidine derivatives were designed and synthesized as candidate human histamine type 3 agonists. The piperazine derivatives were found to have low (or no) affinity for human histamine H3 receptor, where