123994-71-8 Usage
Potential pharmacological applications
Treatment of Parkinson's disease
Treatment of multiple sclerosis
Treatment of different types of cancer
Pharmacological properties
Potent and selective adenosine A2A receptor antagonist
Modulation of dopamine signaling
Inhibition of tumor growth
Significance in medicinal chemistry
Extensively investigated for drug discovery purposes
Promising candidate for therapeutic use in various conditions
Check Digit Verification of cas no
The CAS Registry Mumber 123994-71-8 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 1,2,3,9,9 and 4 respectively; the second part has 2 digits, 7 and 1 respectively.
Calculate Digit Verification of CAS Registry Number 123994-71:
(8*1)+(7*2)+(6*3)+(5*9)+(4*9)+(3*4)+(2*7)+(1*1)=148
148 % 10 = 8
So 123994-71-8 is a valid CAS Registry Number.
123994-71-8Relevant articles and documents
Structure-Activity Relationships of N2-Substituted Guanines as Inhibitors of HSV1 and HSV2 Thymidine Kinases
Hildebrand, Catherine,Sandoli, Daniele,Focher, Federico,Gambino, Joseph,Ciarrocchi, Giovanni,et al.
, p. 203 - 206 (2007/10/02)
A series of N2-phenylguanines was synthesized and tested for inhibition of the thymidine kinases encoded by Herpes simplex viruses type 1 and type 2.Compounds with hydrophobic, electron-attracting groups in the meta position of the phenyl ring