123994-84-3 Usage
Classification
Synthetic purine nucleoside analog
Type of compound
Antineoplastic agent
Mechanism of action
Inhibits DNA polymerase
Inhibits ribonucleotide reductase
Disrupts DNA replication and repair
Induces apoptosis in cancer cells
Efficacy
Effective in treating acute lymphoblastic leukemia (ALL)
Approved for use in pediatric patients with relapsed or refractory ALL
Administration route
Intravenous
Safety and tolerability
Demonstrated good tolerability and safety
Potential applications
Treatment of various types of cancer
Check Digit Verification of cas no
The CAS Registry Mumber 123994-84-3 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 1,2,3,9,9 and 4 respectively; the second part has 2 digits, 8 and 4 respectively.
Calculate Digit Verification of CAS Registry Number 123994-84:
(8*1)+(7*2)+(6*3)+(5*9)+(4*9)+(3*4)+(2*8)+(1*4)=153
153 % 10 = 3
So 123994-84-3 is a valid CAS Registry Number.
123994-84-3Relevant articles and documents
Method for treating disease or condition susceptible to amelioration by AMPK activators and compounds of formula which are useful to activate AMP-activated protein kinase (AMPK)
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Paragraph 0061-0062, (2014/10/16)
The present invention relates to a method for treating disease or condition susceptible to amelioration by AMPK activators and compounds of formula which are useful to activate AMP-activated protein kinase (AMPK) and the use of the compounds in the prevention or treatment of disease, including pre-diabetes, type 2 diabetes, syndrome X, metabolic syndrome and obesity.