1240089-88-6

Basic information

• Product Name: 3-(2,5-dimethoxy-3,4-methylenedioxyphenyl)-5-(3-hydroxy-4-methoxyphenyl)-1,2,4-oxadiazole
• CAS NO: 1240089-88-6
• Molecular Weight: 372.334
• Mol File: 1240089-88-6.mol
• Article Data: 2

Chemical Properties

• CAS DataBase Reference: 3-(2,5-dimethoxy-3,4-methylenedioxyphenyl)-5-(3-hydroxy-4-methoxyphenyl)-1,2,4-oxadiazole(CAS DataBase Reference)
• NIST Chemistry Reference: 3-(2,5-dimethoxy-3,4-methylenedioxyphenyl)-5-(3-hydroxy-4-methoxyphenyl)-1,2,4-oxadiazole(1240089-88-6)
• EPA Substance Registry System: 3-(2,5-dimethoxy-3,4-methylenedioxyphenyl)-5-(3-hydroxy-4-methoxyphenyl)-1,2,4-oxadiazole(1240089-88-6)

Safety Data

• Hazardous Substances Data: 1240089-88-6(Hazardous Substances Data)

Upstream product

• 1119392-76-5 2,5-dimethoxy-3,4-methylenedioxybenzamidoxime 
• 484-52-6 isoapiole 
• 17055-09-3 4,7-dimethoxy-benzo[1,3]dioxole-5-carbaldehyde 
• 523-80-8 apiol 
• 645-08-9 Isovanillic acid 

Relevant articles and documents

Polyalkoxybenzenes from plant raw materials 4. Parsley and dill seed extracts in the synthesis of polyalkoxy-3,5-diaryl-1,2,4-oxadiazoles with antiproliferative activity

Polyalkoxy-5-(4-hydroxyphenyl)-3-phenyl-1,2,4-oxadiazoles were prepared from allylpolyalkoxybenzenes, the main metabolites of parsley and dill seeds. Due to the spatial arrangement of the aryl substituents provided by 1,2,4-oxadiozole fragment, these compounds can be considered as structural analogs of natural antimitotic combretastatins. The antimitotic activity of the synthesized compounds was evaluated in vivo using sea urchin embryo test.