1240390-02-6

Basic information

• Product Name: hydroxy[4-(trifluoromethyl)phenyl]-λ³-iodaneyl 4-methylbenzenesulfonate
• Synonyms: hydroxy[4-(trifluoromethyl)phenyl]-λ³-iodaneyl 4-methylbenzenesulfonate
• CAS NO: 1240390-02-6
• Molecular Weight: 460.213
• Mol File: 1240390-02-6.mol
• Article Data: 3

Chemical Properties

• CAS DataBase Reference: hydroxy[4-(trifluoromethyl)phenyl]-λ³-iodaneyl 4-methylbenzenesulfonate(CAS DataBase Reference)
• NIST Chemistry Reference: hydroxy[4-(trifluoromethyl)phenyl]-λ³-iodaneyl 4-methylbenzenesulfonate(1240390-02-6)
• EPA Substance Registry System: hydroxy[4-(trifluoromethyl)phenyl]-λ³-iodaneyl 4-methylbenzenesulfonate(1240390-02-6)

Safety Data

• Hazardous Substances Data: 1240390-02-6(Hazardous Substances Data)

Upstream product

• 455-13-0 4-Iodobenzotrifluoride 
• 104-15-4 toluene-4-sulfonic acid 

Downstream Products

• 97899-38-2 (2-oxo-1,3-oxazolidin-5-yl)-methyl 4-methylbenzenesulfonate 
• 1174895-53-4 2-(4′-(trifluoromethyl)-[1,1′-biphenyl]-2-yl)pyridine 
• 1240390-03-7 mesityl(4-(trifluoromethyl)phenyl)iodonium 4-methylbenzenesulfonate 

Relevant articles and documents

Continuous-Flow Electrochemical Generator of Hypervalent Iodine Reagents: Synthetic Applications

An efficient and reliable electrochemical generator of hypervalent iodine reagents has been developed. In the anodic oxidation of iodoarenes to hypervalent iodine reagents under flow conditions, the use of electricity replaces hazardous and costly chemical oxidants. Unstable hypervalent iodine reagents can be prepared easily and coupled with different substrates to achieve oxidative transformations in high yields. The unstable, electrochemically generated reagents can also easily be transformed into classic bench-stable hypervalent iodine reagents through ligand exchange. The combination of electrochemical and flow-chemistry advantages largely improves the ecological footprint of the overall process compared to conventional approaches.

Facile synthesis of Koser's reagent and derivatives from iodine or aryl iodides

The first one-pot synthesis of neutral and electron-rich [hydroxy(tosyloxy)iodo]arenes (HTIBs) from iodine and arenes is presented, thereby avoiding the need for expensive iodine(III) precursors. A large set of HTIBs, including a polyfluorinated analogue, can be obtained from the corresponding aryl iodide under the same conditions. The reaction proceeds under mild conditions, without excess reagents, and is fast and high-yielding. Together, the two presented routes give access to a wide range of HTIBs, which are useful reagents in a variety of synthetic transformations.