1240521-70-3

Basic information

• Product Name: (R)-1-fluoro-1-oxo-3-phenylpropan-2-yl acetate
• Synonyms: (R)-1-fluoro-1-oxo-3-phenylpropan-2-yl acetate
• CAS NO: 1240521-70-3
• Molecular Weight: 210.205
• Mol File: 1240521-70-3.mol
• Article Data: 2

Chemical Properties

• CAS DataBase Reference: (R)-1-fluoro-1-oxo-3-phenylpropan-2-yl acetate(CAS DataBase Reference)
• NIST Chemistry Reference: (R)-1-fluoro-1-oxo-3-phenylpropan-2-yl acetate(1240521-70-3)
• EPA Substance Registry System: (R)-1-fluoro-1-oxo-3-phenylpropan-2-yl acetate(1240521-70-3)

Safety Data

• Hazardous Substances Data: 1240521-70-3(Hazardous Substances Data)

Upstream product

• 146235-25-8 (2R)-2-acetoxy-3-phenylpropanoic acid 

Downstream Products

• 1240521-71-4 (R)-1-(2-methoxy-5-(pyridine-4-yl)pyridine-3-ylamino)-1-oxo-3-phenylpropan-2-yl acetate 
• 1401460-36-3 C₃₁H₃₄N₆O₂ 
• 1401460-35-2 C₂₉H₂₇N₅O₄ 
• 1401460-44-3 C₃₃H₃₅N₅O₄ 
• 1401460-34-1 C₂₆H₂₅N₅O₂S 
• 1401460-33-0 C₂₆H₂₄N₆O₂ 
• 1240523-28-7 C₂₇H₂₅N₅O₂ 
• 1401460-32-9 C₂₇H₂₇N₅O₂ 
• 1401460-29-4 C₂₆H₂₅N₅O₂ 
• 1401460-28-3 C₂₄H₂₅N₅O₃ 
• 1401460-23-8 C₂₄H₂₂N₆O₂ 
• 1240523-30-1 (S)-N-(2-methoxy-5-(pyridin-4-yl)pyridin-3-yl)-2-(1-(2-methylthiazol-4-yl)cyclopropylamino)-3-phenylpropanamide 
• 1240523-32-3 (S)-N-(2-methoxy-5-(pyridin-4-yl)pyridin-3-yl)-3-phenyl-2-(1-(pyrimidin-2-yl)cyclopropylamino)propanamide 
• 1240521-74-7 (S)-N-(2-methoxy-5-(pyridin-4-yl)pyridin-3-yl)-3-phenyl-2-(1-(pyridin-2-yl)cyclopropylamino)propanamide 

Relevant articles and documents

Phenylalanine derivatives as GPR142 agonists for the treatment of Type II diabetes

GPR142 is a novel GPCR that is predominantly expressed in pancreatic β-cells. GPR142 agonists potentiate glucose-dependent insulin secretion, and therefore can reduce the risk of hypoglycemia. Optimization of our lead pyridinone-phenylalanine series led to a proof-of-concept compound 22, which showed in vivo efficacy in mice with dose-dependent increase in insulin secretion and a decrease in glucose levels.