1240581-00-3

Basic information

• Product Name: C₂₁H₂₅NO₆
• CAS NO: 1240581-00-3
• Molecular Weight: 387.433
• Mol File: 1240581-00-3.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: C₂₁H₂₅NO₆(CAS DataBase Reference)
• NIST Chemistry Reference: C₂₁H₂₅NO₆(1240581-00-3)
• EPA Substance Registry System: C₂₁H₂₅NO₆(1240581-00-3)

Safety Data

• Hazardous Substances Data: 1240581-00-3(Hazardous Substances Data)

Upstream product

• 22610-64-6 4-acetyl-sinomenine 
• 1240580-97-5 4-acetyl-10-oxosinomenine 

Downstream Products

• 1240581-08-1 C₁₉H₂₃NO₅ 

Relevant articles and documents

SINOMENINE DERIVATIVES, SYNTHETIC METHODS AND USES THEREOF

The invention relates to sinomenine derivatives, methods for their synthesis and their applications. The sinomenine derivatives include oxidation derivatives, and C-10 substituted sinomenine derivatives. Based on the readily oxidizable phenol group on sinomenine structure, using oxidation, oxidative dearomatization, or conjugated addition aromatization, one can introduce C-10 substitutions to synthesize the sinomenine derivatives. The sinomenine derivatives of the invention have the following structures: Using in vitro TNF-α inhibition assay, the activities of the synthetic compounds are assessed. Results from these assays shown that most compounds have anti-inflammatory effects, and some compounds have better activities than that of sinomenine. These compounds may be used in treating immune diseases such as rheumatoid arthritis (RA).