1240816-17-4

Basic information

• Product Name: (S)-2-(2-(4-chlorophenyl)-3-methylbutan-2-yl)-4,4,5,5-tetramethyl-1,3,2-dioxaborolane
• Synonyms: (S)-2-(2-(4-chlorophenyl)-3-methylbutan-2-yl)-4,4,5,5-tetramethyl-1,3,2-dioxaborolane
• CAS NO: 1240816-17-4
• Molecular Weight: 308.656
• Mol File: 1240816-17-4.mol
• Article Data: 2

Chemical Properties

• CAS DataBase Reference: (S)-2-(2-(4-chlorophenyl)-3-methylbutan-2-yl)-4,4,5,5-tetramethyl-1,3,2-dioxaborolane(CAS DataBase Reference)
• NIST Chemistry Reference: (S)-2-(2-(4-chlorophenyl)-3-methylbutan-2-yl)-4,4,5,5-tetramethyl-1,3,2-dioxaborolane(1240816-17-4)
• EPA Substance Registry System: (S)-2-(2-(4-chlorophenyl)-3-methylbutan-2-yl)-4,4,5,5-tetramethyl-1,3,2-dioxaborolane(1240816-17-4)

Safety Data

• Hazardous Substances Data: 1240816-17-4(Hazardous Substances Data)

Upstream product

• 3391-10-4 (S)-1-(4-Chlorophenyl)ethanol 
• 1108740-06-2 (S)-N,N-diisopropyl O-[1-(4-chlorophenyl)]ethyl carbamate 
• 76347-13-2 2-isopropyl-4,4,5,5-tetramethyl-1,3,2-dioxaborolane 
• 106-95-6 allyl bromide 

Downstream Products

• 1240816-19-6 (R)-2-(4-chlorophenyl)-3-methylbutan-2-ol 
• 1272031-49-8 C₁₈H₂₂ClN 

Relevant articles and documents

Addressing the configuration stability of lithiated secondary benzylic carbamates for the development of a noncryogenic stereospecific boronate rearrangement

A practical noncryogenic process for the Aggarwal stereospecific boronate rearrangement with chiral secondary benzylic carbamates has been developed. The use of LDA instead of sec-BuLi combined with an in situ trapping of the unstable lithiated carbamate was critical to success. Furthermore, this new process increased the substrate scope to include the versatile aryl iodide and bromide substrates. The methodology was applied to a diverse array of substrates and was demonstrated on multikilogram scale.