124083-43-8

Basic information

• Product Name: 5-(4-methoxyphenyl)-1,2-dihydro-3H-pyrazol-3-one
• CAS NO: 124083-43-8
• Molecular Formula: C₁₀H₁₀N₂O₂
• Molecular Weight: 190.1986
• Mol File: 124083-43-8.mol
• Article Data: 2

Chemical Properties

• Boiling Point: 461°C at 760 mmHg
• Flash Point: 232.6°C
• Density: 1.213g/cm³
• Vapor Pressure: 4.03E-09mmHg at 25°C
• Refractive Index: 1.569
• CAS DataBase Reference: 5-(4-methoxyphenyl)-1,2-dihydro-3H-pyrazol-3-one(CAS DataBase Reference)
• NIST Chemistry Reference: 5-(4-methoxyphenyl)-1,2-dihydro-3H-pyrazol-3-one(124083-43-8)
• EPA Substance Registry System: 5-(4-methoxyphenyl)-1,2-dihydro-3H-pyrazol-3-one(124083-43-8)

Safety Data

• Hazardous Substances Data: 124083-43-8(Hazardous Substances Data)

Upstream product

• 2881-83-6 ethyl 4-methoxybenzoylacetate 
• 100-07-2 4-methoxy-benzoyl chloride 

Downstream Products

• 7515-17-5 methyl 3-(4-methoxyphenyl)propynoate 

Relevant articles and documents

Synthesis of 3-substituted and 3,4-disubstituted pyrazolin-5-ones

The synthesis of 3-substituted and 3,4-disubstituted pyrazolin-5-ones from acylated ethyl acetoacetates and diethyl malonates is described. The reaction of acylated ethyl acetoacetates and diethyl acetylmalonate with hydrazine (98%) gave 3-substituted pyrazolin-5-ones and malonyldihydrazide, respectively, following a deacetylation-condensation sequence. The reaction of ethyl 2-acetyl-3-hydroxy-2-butenoate and diethyl 2-(1-hydroxyethylidene)malonate with hydrazine monohydrochloride yielded ethyl 3,5-dimethyl-1H-pyrazole-4-carboxylate and 4-ethoxycarbonyl-3-methylpyrazolin-5-one, respectively, following a dehydration-cyclocondensation sequence, in high yields.