1240893-76-8

Basic information

• Product Name: tert-butyl 2-(4,5-dibromo-1H-imidazol-2-yl)pyrrolidine-1-carboxylate
• Synonyms: tert-butyl 2-(4,5-dibromo-1H-imidazol-2-yl)pyrrolidine-1-carboxylate;tert-butyl (S)-2-(4, 5-dibromo-1H-imidazol-2-yl)pyrrolidine-1-carboxylate;1-Pyrrolidinecarboxylic acid, 2-(4,5-dibromo-1H-imidazol-2-yl)-, 1,1-dimethylethyl ester, (2S)-;(S)-tert-butyl 2-(4,5-dibromo-1H-imidazol-2-yl)pyrrolidine-1-carboxylate
• CAS NO: 1240893-76-8
• Molecular Formula: C₁₂H₁₇Br₂N₃O₂
• Molecular Weight: 395.09028
• Mol File: 1240893-76-8.mol
• Article Data: 17

Chemical Properties

• Appearance: /
• CAS DataBase Reference: tert-butyl 2-(4,5-dibromo-1H-imidazol-2-yl)pyrrolidine-1-carboxylate(CAS DataBase Reference)
• NIST Chemistry Reference: tert-butyl 2-(4,5-dibromo-1H-imidazol-2-yl)pyrrolidine-1-carboxylate(1240893-76-8)
• EPA Substance Registry System: tert-butyl 2-(4,5-dibromo-1H-imidazol-2-yl)pyrrolidine-1-carboxylate(1240893-76-8)

Safety Data

• Hazardous Substances Data: 1240893-76-8(Hazardous Substances Data)

Usage

General Description

Tert-butyl 2-(4,5-dibromo-1H-imidazol-2-yl)pyrrolidine-1-carboxylate is a synthetic compound with a complex chemical structure. It is classified as an ester, containing a pyrrolidine ring and a 4,5-dibromo-1H-imidazol-2-yl substituent. This chemical is commonly used in the research and development of pharmaceuticals and agrochemicals, as well as in the synthesis of novel organic molecules. Its unique structure and properties make it a valuable component in the creation of new medicines and chemical compounds. Additionally, it has potential applications in the field of organic chemistry, where it can be utilized in various reactions and transformations to produce diverse products.

Upstream product

• 1007882-58-7 (S)-tert-butyl 2-(1H-imidazol-2-yl)pyrrolidine-1-carboxylate 
• 69610-40-8 N-(tert-butoxycarbonyl)-L-prolinol 
• 69610-41-9 Boc-L-Pro-H 
• 1007882-59-8 (S)-2-(4-bromo-1H-imidazol-2-yl)pyrrolidine-1-carboxylic acid tert-butyl ester 
• 15761-39-4 1-(tert-butoxycarbonyl)-L-proline 

Downstream Products

• 1007882-59-8 (S)-2-(5-bromo-1H-imidazol-2-yl)pyrrolidine-1-carboxylic acid tert-butyl ester 
• 1007882-59-8 (S)-2-(4-bromo-1H-imidazol-2-yl)pyrrolidine-1-carboxylic acid tert-butyl ester 
• 1292836-05-5 methyl ((S)-1-((S)-2-(4-bromo-1H-imidazol-2-yl)pyrrolidin-1-yl)-3-methyl-1-oxobutan-2-yl)carbamate 
• 1370647-67-8 C₅₂H₅₇N₉O₈ 
• 1370647-84-9 C₅₂H₆₁N₉O₈ 
• 1369595-25-4 C₃₄H₃₂Cl₂N₄O₄ 
• 1369595-29-8 C₄₅H₄₈ClN₇O₅ 
• 1369595-30-1 C₅₀H₅₃N₇O₅S 
• 1369595-32-3 C₅₁H₅₃N₇O₅ 
• 1369996-08-6 C₄₁H₃₇N₇O 
• 1369595-41-4 C₄₆H₅₀FN₇O₆ 
• 1369595-45-8 C₄₇H₅₃N₇O₇ 
• 1392101-95-9 C₅₁H₅₉N₉O₉ 
• 1370624-48-8 C₅₁H₅₉N₉O₉ 

Relevant articles and documents

INHIBITORS OF HEPATITIS C VIRUS REPLICATION

The present invention relates to compounds of formula (I) that are useful as hepatitis C virus (HCV) NS5A inhibitors, the synthesis of such compounds, and the use of such compounds for inhibiting HCV NS5A activity, for treating or preventing HCV infections and for inhibiting HCV viral replication and/or viral production in a cell-based system.

9,9,10,10-TETRAFLUORO-9,10-DIHYDROPHENANTHRENE HEPATITIS C VIRUS INHIBITOR AND APPLICATION THEREOF

The present invention belongs to the field of chemical pharmaceuticals, and specifically relates to compounds represented by formula I having a 9,9,10,10-tetrafluoro-9,10-dihydrophenanthrene structure and being able to inhibit hepatitis C virus activity, or a pharmaceutically acceptable salt, isomer, solvate, crystal or prodrug of said compounds, a pharmaceutical composition containing said compounds, and an application of said compounds or composition in the preparation of a drug. The compounds of the present invention have a good HCV inhibitory effect.

Discovery of thienoimidazole-based HCV NS5A inhibitors. Part 1: C2-Symmetric inhibitors with diyne and biphenyl linkers

The discovery of C2-symmetric bis-thienoimidazoles HCV NS5A inhibitors is herein reported. Two straightforward approaches to access the requisite diyne and biphenyl linker moieties are described. This study revealed the paramount importance of the aromatic character of the linker to achieve high genotype 1a potency.