124107-39-7 Usage
Description
Pregnanolone sulfate pyridinium salt, also known as (3α)-Pregnanolone sulfate, is an endogenous neurosteroid derived from (3α)-Pregnanolone. It possesses neuroprotective properties and is known for its ability to inhibit N-methyl-D-aspartate (NMDA) receptors, which play a crucial role in the central nervous system.
Uses
Used in Pharmaceutical Industry:
Pregnanolone sulfate pyridinium salt is used as a neuroprotective agent for its ability to inhibit NMDA receptors, which can help protect neurons from damage and degeneration. This makes it a promising candidate for the treatment of various neurological disorders and conditions associated with neuronal damage.
Used in Neurological Research:
In the field of neuroscience, pregnanolone sulfate pyridinium salt is used as a research tool to study the function and role of NMDA receptors in the central nervous system. By inhibiting these receptors, researchers can gain insights into the underlying mechanisms of various neurological conditions and develop targeted therapies.
Used in Drug Development:
Pregnanolone sulfate pyridinium salt is utilized in the development of new drugs aimed at treating neurological disorders. Its neuroprotective properties and ability to modulate NMDA receptor activity make it a valuable compound for designing and testing potential therapeutic agents.
Check Digit Verification of cas no
The CAS Registry Mumber 124107-39-7 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 1,2,4,1,0 and 7 respectively; the second part has 2 digits, 3 and 9 respectively.
Calculate Digit Verification of CAS Registry Number 124107-39:
(8*1)+(7*2)+(6*4)+(5*1)+(4*0)+(3*7)+(2*3)+(1*9)=87
87 % 10 = 7
So 124107-39-7 is a valid CAS Registry Number.
124107-39-7Relevant articles and documents
Synthesis of C3, C5, and C7 pregnane derivatives and their effect on NMDA receptor responses in cultured rat hippocampal neurons
Stastna, Eva,Chodounska, Hana,Pouzar, Vladimir,Kapras, Vojtech,Borovska, Jirina,Cais, Ondrej,Vyklicky Jr., Ladislav
, p. 256 - 263 (2009)
The synthesis of several novel 5α- and 5β-20-oxo-pregnane derivatives substituted in the position 3 and 7 of the steroid skeleton is described. Activity of synthesized compounds was studied in voltage-clamped cultured rat hippocampal neurons. Substituted