1241388-95-3

Basic information

• Product Name: 5-(1-(4-fluorophenyl)-3-oxobutyl)furan-2(5H)-one
• Synonyms: 5-(1-(4-fluorophenyl)-3-oxobutyl)furan-2(5H)-one
• CAS NO: 1241388-95-3
• Molecular Weight: 248.254
• Mol File: 1241388-95-3.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: 5-(1-(4-fluorophenyl)-3-oxobutyl)furan-2(5H)-one(CAS DataBase Reference)
• NIST Chemistry Reference: 5-(1-(4-fluorophenyl)-3-oxobutyl)furan-2(5H)-one(1241388-95-3)
• EPA Substance Registry System: 5-(1-(4-fluorophenyl)-3-oxobutyl)furan-2(5H)-one(1241388-95-3)

Safety Data

• Hazardous Substances Data: 1241388-95-3(Hazardous Substances Data)

Upstream product

• 65300-29-0 4-(4-fluorophenyl)but-3-en-2-one 
• 497-23-4 2-buten-4-olide 

Relevant articles and documents

Asymmetric vinylogous Michael reaction of α,β-unsaturated ketones with γ-butenolide under multifunctional catalysis

A general and direct organocatalytic asymmetric vinylogous Michael reaction of γ-butenolide with α,β-unsaturated ketones was investigated with a multifunctional primary amine salt as catalyst. The reaction enables straightforward access toward synthetically versatile γ-substituted butenolides from simple 2(5H)-furanone with satisfactory yields, diastereo- and enantioselectivities (up to 30:1 dr and 95-99% ee).