1241906-58-0

Basic information

• Product Name: sodium [(2,3-difluorobenzyl) 5-acetamido-9-(4-chlorobenzamido)-3,5,9-trideoxy-7,8-O-isopropylidene-4-O-(2-(2-thienyl)ethylcarbamoyl)-D-glycero-α-D-galacto-2-nonulopyranosid]onate
• Synonyms: sodium [(2,3-difluorobenzyl) 5-acetamido-9-(4-chlorobenzamido)-3,5,9-trideoxy-7,8-O-isopropylidene-4-O-(2-(2-thienyl)ethylcarbamoyl)-D-glycero-α-D-galacto-2-nonulopyranosid]onate
• CAS NO: 1241906-58-0
• Molecular Weight: 788.198
• Mol File: 1241906-58-0.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: sodium [(2,3-difluorobenzyl) 5-acetamido-9-(4-chlorobenzamido)-3,5,9-trideoxy-7,8-O-isopropylidene-4-O-(2-(2-thienyl)ethylcarbamoyl)-D-glycero-α-D-galacto-2-nonulopyranosid]onate(CAS DataBase Reference)
• NIST Chemistry Reference: sodium [(2,3-difluorobenzyl) 5-acetamido-9-(4-chlorobenzamido)-3,5,9-trideoxy-7,8-O-isopropylidene-4-O-(2-(2-thienyl)ethylcarbamoyl)-D-glycero-α-D-galacto-2-nonulopyranosid]onate(1241906-58-0)
• EPA Substance Registry System: sodium [(2,3-difluorobenzyl) 5-acetamido-9-(4-chlorobenzamido)-3,5,9-trideoxy-7,8-O-isopropylidene-4-O-(2-(2-thienyl)ethylcarbamoyl)-D-glycero-α-D-galacto-2-nonulopyranosid]onate(1241906-58-0)

Safety Data

• Hazardous Substances Data: 1241906-58-0(Hazardous Substances Data)

Upstream product

• 58749-51-2 2-(thiophen-2-yl)ethyl isocynate 
• 1241906-48-8 sodium [(2,3-difluorobenzyl) 5-acetamido-9-(4-chlorobenzamido)-3,5,9-trideoxy-7,8-O-isopropylidene-D-glycero-α-D-galacto-2-nonulopyranosid]onate 

Downstream Products

• 1241906-66-0 sodium [(2,3-difluorobenzyl) 5-acetamido-9-(4-chlorobenzamido)-3,5,9-trideoxy-4-O-(2-(2-thienyl)ethylcarbamoyl)-D-glycero-α-D-galacto-2-nonulopyranosid]onate 

Relevant articles and documents

Kinetic and thermodynamic properties of MAG antagonists

Paraplegia is caused by injuries of the central nervous system (CNS) and especially young people suffer from these severe consequences as, for example, the loss of motor functions. The lack of repair of the injured nerve strands originates from the inhibitory environment for axon regeneration in the CNS. Specific inhibitory proteins block the regrowth of nerve roots. One of these neurite outgrowth inhibitors is the myelin-associated glycoprotein (MAG), which is a member of the Siglec family (sialic acid-binding immunoglobulin-like lectin). In previous studies, we identified potent small molecule MAG antagonists. In this communication, we report new neuraminic acid derivatives modified in the 4- and 5-position, and the influence of various structural modifications on their kinetic and thermodynamic binding properties.