1241960-10-0

Basic information

• Product Name: (4S)-4-benzyl-3-[(trifluoromethoxy)acetyl]-1,3-oxazolidin-2-one
• Synonyms: (4S)-4-benzyl-3-[(trifluoromethoxy)acetyl]-1,3-oxazolidin-2-one
• CAS NO: 1241960-10-0
• Molecular Weight: 303.238
• Mol File: 1241960-10-0.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: (4S)-4-benzyl-3-[(trifluoromethoxy)acetyl]-1,3-oxazolidin-2-one(CAS DataBase Reference)
• NIST Chemistry Reference: (4S)-4-benzyl-3-[(trifluoromethoxy)acetyl]-1,3-oxazolidin-2-one(1241960-10-0)
• EPA Substance Registry System: (4S)-4-benzyl-3-[(trifluoromethoxy)acetyl]-1,3-oxazolidin-2-one(1241960-10-0)

Safety Data

• Hazardous Substances Data: 1241960-10-0(Hazardous Substances Data)

Upstream product

• 3582-05-6 trifluoromethyl trifluoromethanesulfonate 
• 129549-13-9 4S-3-(2-bromoacetyl)-4-(phenylmethyl)-2-oxazolidinone 
• 1241960-12-2 (S)-4-benzyl-3-(2-iodoacetyl)oxazolidin-2-one 

Relevant articles and documents

A deeper insight into direct trifluoromethoxylation with trifluoromethyl triflate

Commercially available fluorides (silver fluoride and n-tetrabutylammonium triphenyldifluorosilicate), combined with TFMT, allow a simple generation, in situ, of silver and n-tetrabutylammonium trifluoromethoxides which were able to react with electrophilic substrates. Silver trifluoromethoxide, which is usually more efficient than n-tetrabutylammonium trifluoromethoxide, converts, under mild conditions, primary aliphatic bromides and iodides, as well as primary and secondary benzylic or allylic bromides to the corresponding trifluoromethoxylated compounds. Several trifluoromethyl ethers, which could be valuable building-blocks, were prepared in such a way.